NIH Common Fund Metabolomics Funded Research

Projects funded since the inception of this program can be found at

Pilot and Feasibility Program

Pilot and Feasibility P&F awards are intended to provide opportunities for investigators to advance basic, clinical and translational biomedical science by incorporating metabolomic technologies into their research, and to support projects that will provide preliminary data for new extramural proposal submission.

Please see our Pilot and Feasibility Program page for a list of funded Pilot and Feasibility studies.

Comprehensive Metabolomics Resource Cores

Goal: To create National Comprehensive Metabolomics Resource Cores, expanding on existing nationally funded metabolomics resources.

Regional Comprehensive Metabolomics Resource Cores (RCMRC) (U24) RFA-RM-11-016

PI Name Institution Name Title

Burant, Charles F

University of Michigan at Ann Arbor

Michigan Regional Comprehensive Metabolomics Resource Core (MRC2)

Fiehn, Oliver

University of California Davis

West Coast Central Comprehensive Metabolomics Resource Core (WCMC)

Sumner, Susan J

Research Triangle Institute

RTI's Regional Comprehensive Metabolomics Resource Center

Edison, Arthur S (contact)
Yost, Richard A.

University of Florida

Southeast Resource Center for Integrated Metabolomics (SECIM)

Higashi, Richard M (contact)
Fan, Teresa W-M
Lane, Andrew N
Moseley, Hunter Nathaniel

University of Kentucky

Resource Center for Stable Isotope-Resolved Metabolomics

Nair, K Sreekumaran

Mayo Clinic

Mayo Clinic Metabolomics Resource Core

Training in Metabolomics

Goal: To increase the number of investigators with metabolomics expertise by supporting interdisciplinary training involving a diverse set of training vehicles that match career stage and goals.

Development of Courses or Workshops in Metabolomics (R25) RFA-RM-11-018

PI Name Institution Name Title

Barnes, Stephen

University of Alabama at Birmingham

UAB Metabolomics Workshop: from design to decision

Kohlmeier, Martin

University of North Carolina Chapel Hill

Online learning platform: introducing clinicians and researchers to metabolomics

Mentored Research Scientist Development Award in Metabolomics (K01) RFA-RM-11-017

PI Name Institution Name Title

Ammons, Mary Cloud Bosworth

Montana State University - Bozeman

Metabolomic Analysis as a Tool to Understanding the Use of Novel Therapeutics in

Ngo, Debby

Massachusetts General Hospital

The Kynurenine Pathway in Pulmonary Arterial Hypertension

Phelan, Vanessa V

University of California San Diego

The Interactive Metabolome of Polymicrobial Biofilms

Rowley, Jesse

University of Utah

The Platelet Metabolome in Obesity


Mentored Research Scientist Development Award in Metabolomics (K01) RFA-RM-12-025

PI Name Institution Name Title

Gooding, Jessica

Duke University

Metabolic Regulators of Insulin Secretion and Insulin Resistance

Grossmann, Ruth Elizabeth

University of Iowa

Metabolomic Biomarkers of a Nutritional Intervention to Prevent Weight Gain

Mitsche, Matthew Alvin

UT Southwestern Medical Center

Determining the Function of PNPLA3 Utilizing Metabolomics and Stable Isotope Labe

Theriot, Casey

University of Michigan

Shifts in the Gastrointestinal Metabolome During Clostridium difficile Infection

Viader, Andreu

Scripps Research Institute

Lipidomic mapping of the cellular anatomy of brain endocannabinoid metabolism

Yim, Sun Hee

Brigham and Women's Hospital

Metabolomics of Aging

Metabolomics Technology Development

Goal: To address current limitations in metabolomics technologies so they can be easily adapted by other laboratories.

Technology Development to Enable Large Scale Metabolomics Analyses (R01) RFA-RM-11-019

PI Name Institution Name Title

Baker, Erin S

Battelle Pacific Northwest Laboratories

Platform Providing Increased Throughput, Sensitivity and Specificity for Metabolo

Fan, Teresa W-M (contact)
Higashi, Richard M
Moseley, Hunter Nathaniel
Nantz, Michael H

University of Louisville

Integrated Chemoselective and Informatic Platform for Large-Scale Metabolomics

Hu, Jian Zhi

Battelle Pacific Northwest Laboratories

Slow-MAS NMR Metabolomics

Murphy, Robert Carl

University of Colorado Denver

High Throughput Lipidomics Analysis by MALDI/Ion Mobility Mass Spectrometry

Patterson, Andrew

Pennsylvania State University-UNIV Park

Optimized Metabolite Extraction, Separation, and Identification for Metabolomics

Patti, Gary Joseph

Washington University

Developing the Untargeted Metabolomic Workflow for High-Throughput Analyses

Metabolomics Reference Standards Synthesis

Goal: To increase the repertoire of chemically identifiable metabolites through the synthesis of reliable metabolic standards.

Synthesis contracts have been awarded to RTI International and SRI International and synthesis pilot studies with select metabolites are underway.

Data Sharing and International Collaboration

Data sharing and international collaboration are important aspects of the Metabolomics Research Capacity program, and will be accomplished via the Metabolomics Workbench.

Metabolomics Data Repository and Coordinating Center (U01) RFA-RM-11-020

PI Name Institution Name Title

Subramaniam, Shankar

University of California San Diego

The Metabolomics Data Center and Workbench (MDCW)

Administrative Supplement Program

Since 2012, the NIH has issued an annual solicitation for Administrative Supplements to existing NIH grants to form new interactive collaborations between basic or clinical researchers and metabolomics experts to add a metabolomics approach to the existing Research Strategy for the project. In addition to enhancing the parent grant by adding metabolomics analyses, collaborative projects include activities to increase the expertise of the biomedical research group in key aspects of metabolomics study design, analysis, and data interpretation. Funded projects can be found at