RefMet Compound Details
MW structure | 50056 (View MW Metabolite Database details) | |
---|---|---|
RefMet name | Succinyl-CoA | |
Alternative name | CoA DC4:0 | |
Systematic name | 3'-phosphoadenosine 5'-{3-[(3R)-4-{[3-({2-[(3-carboxypropanoyl)sulfanyl]ethyl}amino)-3-oxopropyl]amino}-3-hydroxy-2,2-dimethyl-4-oxobutyl] dihydrogen diphosphate} | |
SMILES | CC(C)(COP(=O)(O)OP(=O)(O)OC[C@@H]1[C@H]([C@H]([C@H](n2cnc3c(N)ncnc23)O1)O)OP(=O)(O)O)[C@H](C(=O)NCCC(=O)NCCSC(=O)CCC(=O)O)O Run Tanimoto similarity search (with similarity coefficient >=0.6) | |
Sum Composition | CoA 4:1;O2 | View other entries in RefMet with this sum composition |
Exact mass | 867.131264 (neutral) |
Table of KEGG reactions in human pathways involving Succinyl-CoA
Rxn ID | KEGG Reaction | Enzyme |
---|---|---|
R00405 | ATP + Succinate + CoA <=> ADP + Orthophosphate + Succinyl-CoA | Succinate:CoA ligase (ADP-forming) |
R00406 | Succinyl-CoA + (S)-Malate <=> Succinate + L-Malyl-CoA | succinyl-CoA:(S)-malate CoA-transferase |
R00432 | GTP + Succinate + CoA <=> GDP + Orthophosphate + Succinyl-CoA | Succinate:CoA ligase (GDP-forming) |
R00727 | ITP + Succinate + CoA <=> IDP + Orthophosphate + Succinyl-CoA | Succinate:CoA ligase (IDP-forming) |
R00833 | (R)-Methylmalonyl-CoA <=> Succinyl-CoA | (R)-Methylmalonyl-CoA CoA-carbonylmutase |
R01197 | 2 Reduced ferredoxin + Succinyl-CoA + CO2 + 2 H+ <=> 2 Oxidized ferredoxin + 2-Oxoglutarate + CoA | 2-oxoglutarate:ferredoxin oxidoreductase (decarboxylating) |
R08549 | 2-Oxoglutarate + CoA + NAD+ <=> Succinyl-CoA + CO2 + NADH + H+ | 2-Oxoglutarate dehydrogenase complex |
R10343 | Succinyl-CoA + Acetate <=> Acetyl-CoA + Succinate | succinyl-CoA:acetate CoA-transferase |
Table of KEGG human pathways containing Succinyl-CoA
Pathway ID | Human Pathway | # of reactions |
---|---|---|
hsa01200 | Carbon metabolism | 5 |
hsa00020 | Citrate cycle (TCA cycle) | 3 |
hsa00640 | Propanoate metabolism | 3 |
hsa01100 | Metabolic pathways | 3 |
hsa00280 | Valine, leucine and isoleucine degradation | 1 |
hsa00630 | Glyoxylate and dicarboxylate metabolism | 1 |