RefMet Compound Details

MW structure37167 (View MW Metabolite Database details)
RefMet nameSerotonin
Systematic name3-(2-aminoethyl)-1H-indol-5-ol
SMILESc1cc2c(cc1O)c(CCN)c[nH]2   Run Tanimoto similarity search (with similarity coefficient >=0.6)
Exact mass176.094963 (neutral)
Calculate m/z:   
View other RefMet entries with this exact (neutral) mass:   +/- 0.05 amu   +/- 0.1 amu   +/- 0.2 amu   +/- 0.5 amu
FormulaC10H12N2OView other entries in RefMet with this formula
InChIKeyQZAYGJVTTNCVMB-UHFFFAOYSA-NView other enantiomers/diastereomers of this metabolite in RefMet
Super ClassAlkaloids
Main ClassTryptophan alkaloids
Sub ClassTryptamines
Pubchem CID5202
Annotation level1   (1:Known structure; 2:Known regiochemistry; 3:Partial structure; 4:Sum-composition)

Table of KEGG reactions in human pathways involving Serotonin

Rxn IDKEGG ReactionEnzyme
R02701 5-Hydroxy-L-tryptophan <=> Serotonin + CO25-Hydroxy-L-tryptophan decarboxy-lyase
R02911 Acetyl-CoA + Serotonin <=> CoA + N-Acetylserotoninacetyl-CoA:aralkylamine N-acetyltransferase
R02908 Serotonin + H2O + Oxygen <=> 5-Hydroxyindoleacetaldehyde + Ammonia + Hydrogen peroxide5-Hydroxytryptamine:oxygen oxidoreductase(deaminating)(flavin-containing)
R02909 Serotonin + Oxygen <=> Formyl-5-hydroxykynurenamine5-hydroxytryptamine:oxygen 2,3-dioxygenase (indole-decyclizing)
R02910 S-Adenosyl-L-methionine + Serotonin <=> S-Adenosyl-L-homocysteine + N-MethylserotoninS-Adenosyl-L-methionine:amine N-methyltransferase

Table of KEGG human pathways containing Serotonin

Pathway IDHuman Pathway# of reactions
hsa00380 Tryptophan metabolism 5