RefMet Compound Details

MW structure37510 (View MW Metabolite Database details)
RefMet nameS-Adenosylhomocysteine
Systematic name(2S)-2-amino-4-({[(2S,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl}sulfanyl)butanoic acid
SMILESNc1[n]c[n]c2c1[n]c[n]2[C@@H]1O[C@H](CSCC[C@H](N)C(O)=O)[C@@H](O)[C@H]1O
Exact mass384.121591 (neutral)
Calculate m/z:   
View other RefMet entries with this exact (neutral) mass:   +/- 0.05 amu   +/- 0.1 amu   +/- 0.2 amu   +/- 0.5 amu
FormulaC14H20N6O5SView other entries in RefMet with this formula
InChIInChI=1S/C14H20N6O5S/c15-6(14(23)24)1-2-26-3-7-9(21)10(22)13(25-7)20-5-19-8-11(16)17-4-18-12(8)20/h4-7,9-10,13,21-22H,1-3,15H2,(H,
23,24)(H2,16,17,18)/t6-,7+,9+,10+,13+/m0/s1
InChIKeyZJUKTBDSGOFHSH-WFMPWKQPSA-NView other enantiomers/diastereomers of this metabolite in RefMet
Super ClassCarbohydrates
Main ClassGlycosyl compounds
Sub ClassGlycosylamines
Pubchem CID439155
Annotation level1   (1:Known structure; 2:Known regiochemistry; 3:Partial structure; 4:Sum-composition)
Human quantitationView measurements in targeted assays on human samples

Table of KEGG reactions in human pathways involving S-Adenosylhomocysteine

Rxn IDKEGG ReactionEnzyme
R00192 S-Adenosyl-L-homocysteine + H2O <=> Adenosine + L-HomocysteineS-Adenosyl-L-homocysteine hydrolase
R04858 S-Adenosyl-L-methionine + DNA cytosine <=> S-Adenosyl-L-homocysteine + DNA 5-methylcytosineS-adenosyl-L-methionine:DNA (cytosine-5-)-methyltransferase
R10404 S-Adenosyl-L-methionine <=> S-Adenosyl-L-homocysteineS-Adenosyl-L-methionine <=> S-Adenosyl-L-homocysteine

Table of KEGG human pathways containing S-Adenosylhomocysteine

Pathway IDHuman Pathway# of reactions
hsa00270 Cysteine and methionine metabolism 2
hsa01100 Metabolic pathways 1
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