RefMet Compound Details

MW structure50071 (View MW Metabolite Database details)
RefMet nameProtoporphyrin
Systematic name7,12-diethenyl-3,8,13,17-tetramethylporphyrin-2,18-dipropanoic acid
SMILESC=Cc1c(C)c2/C=C\3/C(=C(CCC(=O)O)C(=N3)/C=c\3/c(CCC(=O)O)c(C)/c(=C/C4=N/C(=C\c1[nH]2)/C(=C4C=C)C)/[nH]3)C   Run Tanimoto similarity search (with similarity coefficient >=0.6)
Exact mass562.258006 (neutral)
Calculate m/z:   
View other RefMet entries with this exact (neutral) mass:   +/- 0.05 amu   +/- 0.1 amu   +/- 0.2 amu   +/- 0.5 amu
FormulaC34H34N4O4View other entries in RefMet with this formula
InChIKeyKSFOVUSSGSKXFI-UJJXFSCMSA-NView other enantiomers/diastereomers of this metabolite in RefMet
Super ClassOrganoheterocyclic compounds
Main ClassPorphyrins
Sub ClassPorphyrins
Pubchem CID4971
Annotation level1   (1:Known structure; 2:Known regiochemistry; 3:Partial structure; 4:Sum-composition)

Table of KEGG reactions in human pathways involving Protoporphyrin

Rxn IDKEGG ReactionEnzyme
R00310 Protoporphyrin + Fe2+ <=> Heme + 2 H+protoheme ferro-lyase (protoporphyrin-forming)
R09489 Protoporphyrinogen IX + 3 Menaquinone <=> Protoporphyrin + 3 Menaquinolprotoporphyrinogen IX:menaquinone oxidoreductase
R12605 Protoporphyrinogen IX + 3 Acceptor <=> Protoporphyrin + 3 Reduced acceptorprotoporphyrinogen IX oxidase [EC:1.3.99.-]
R03222 Protoporphyrinogen IX + 3 Oxygen <=> Protoporphyrin + 3 Hydrogen peroxideprotoporphyrinogen-IX:oxygen oxidoreductase

Table of KEGG human pathways containing Protoporphyrin

Pathway IDHuman Pathway# of reactions
hsa00860 Porphyrin and chlorophyll metabolism 2
hsa01100 Metabolic pathways 2
hsa01240 Biosynthesis of cofactors 2