RefMet Compound Details
MW structure | 35438 (View MW Metabolite Database details) | |
---|---|---|
RefMet name | Progesterone | |
Systematic name | pregn-4-ene-3,20-dione | |
SMILES | CC(=O)[C@H]1CC[C@H]2[C@@H]3CCC4=CC(=O)CC[C@]4(C)[C@H]3CC[C@]12C Run Tanimoto similarity search (with similarity coefficient >=0.6) | |
Sum Composition | ST 21:3;O2 | View other entries in RefMet with this sum composition |
Exact mass | 314.224580 (neutral) |
Table of KEGG reactions in human pathways involving Progesterone
Rxn ID | KEGG Reaction | Enzyme |
---|---|---|
R02207 | 20alpha-Hydroxy-4-pregnen-3-one + NAD+ <=> Progesterone + NADH + H+ | 20alpha-Hydroxy-4-pregnen-3-one:NAD+ 20-oxidoreductase |
R02208 | 5alpha-Pregnane-3,20-dione + NADP+ <=> Progesterone + NADPH + H+ | 5alpha-pregnane-3,20-dione:NADP+ delta4-oxidoreductase |
R02209 | 20alpha-Hydroxy-4-pregnen-3-one + NADP+ <=> Progesterone + NADPH + H+ | 20alpha-Hydroxy-4-pregnen-3-one:NADP+ 20-oxidoreductase |
R02211 | Progesterone + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> 17alpha-Hydroxyprogesterone + [Oxidized NADPH---hemoprotein reductase] + H2O | progesterone,NADPH-hemoprotein reductase:oxygen oxidoreductase (17alpha-hydroxylating) |
R02213 | Progesterone + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> 11-Deoxycorticosterone + [Oxidized NADPH---hemoprotein reductase] + H2O | progesterone,NADPH-hemoprotein reductase:oxygen oxidoreductase (21-hydroxylating) |
R02215 | 5beta-Pregnane-3,20-dione + Acceptor <=> Progesterone + Reduced acceptor | 5beta-Pregnane-3,20-dione:(acceptor) delta4-oxidoreductase |
R02216 | Pregnenolone + NAD+ <=> Progesterone + NADH + H+ | Pregnenolone:NAD+ 3-oxidoreductase |
R02218 | Progesterone + 2 Reduced ferredoxin + Oxygen + 2 H+ <=> 11beta-Hydroxyprogesterone + 2 Oxidized ferredoxin + H2O | progesterone,reduced ferredoxin:oxygen oxidoreductase (11-hydroxylating) |
R02219 | Progesterone + NADPH + H+ <=> 5beta-Pregnane-3,20-dione + NADP+ | 3-Oxo-5beta-steroid:NADP+ delta4-oxidoreductase |
Table of KEGG human pathways containing Progesterone
Pathway ID | Human Pathway | # of reactions |
---|---|---|
hsa00140 | Steroid hormone biosynthesis | 8 |
hsa01100 | Metabolic pathways | 3 |