RefMet Compound Details

MW structure37146 (View MW Metabolite Database details)
RefMet nameOrotic acid
Systematic name2,6-dioxo-1,2,3,6-tetrahydropyrimidine-4-carboxylic acid
SMILESOC(=O)C1=CC(=O)NC(=O)N1
Exact mass156.017108 (neutral)
Calculate m/z:   
View other RefMet entries with this exact (neutral) mass:   +/- 0.05 amu   +/- 0.1 amu   +/- 0.2 amu   +/- 0.5 amu
FormulaC5H4N2O4View other entries in RefMet with this formula
InChIInChI=1S/C5H4N2O4/c8-3-1-2(4(9)10)6-5(11)7-3/h1H,(H,9,10)(H2,6,7,8,11)
InChIKeyPXQPEWDEAKTCGB-UHFFFAOYSA-NView other enantiomers/diastereomers of this metabolite in RefMet
Super ClassNucleic acids
Main ClassPyrimidines
Sub ClassPyrimidine carboxylic acids
Pubchem CID967
Annotation level1   (1:Known structure; 2:Known regiochemistry; 3:Partial structure; 4:Sum-composition)

Table of KEGG reactions in human pathways involving Orotic acid

Rxn IDKEGG ReactionEnzyme
R01867 (S)-Dihydroorotate + Fumarate <=> Orotate + Succinate(S)-dihydroorotate:fumarate oxidoreductase
R01868 (S)-Dihydroorotate + Quinone <=> Orotate + Hydroquinone(S)-dihydroorotate:quinone oxidoreductase
R01869 (S)-Dihydroorotate + NAD+ <=> Orotate + H+ + NADH(S)-dihydroorotate:NAD+ oxidoreductase

Table of KEGG human pathways containing Orotic acid

Pathway IDHuman Pathway# of reactions
hsa00240 Pyrimidine metabolism 2
hsa01100 Metabolic pathways 2
hsa01240 Biosynthesis of cofactors 2
  logo