RefMet Compound Details

MW structure553 (View MW Metabolite Database details)
RefMet nameLinoleic acid
Alternative nameFA 18:2(9Z,12Z)
Systematic name9Z,12Z-octadecadienoic acid
SMILESCCCCC/C=C\C/C=C\CCCCCCCC(=O)O   Run Tanimoto similarity search (with similarity coefficient >=0.6)
Sum CompositionFA 18:2 View other entries in RefMet with this sum composition
Exact mass280.240230 (neutral)
Calculate m/z:   
View other RefMet entries with this exact (neutral) mass:   +/- 0.05 amu   +/- 0.1 amu   +/- 0.2 amu   +/- 0.5 amu
FormulaC18H32O2View other entries in RefMet with this formula
InChIKeyOYHQOLUKZRVURQ-HZJYTTRNSA-NView other enantiomers/diastereomers of this metabolite in RefMet
Super ClassFatty Acyls
Main ClassFatty acids
Sub ClassUnsaturated FA
Pubchem CID5280450
Annotation level1   (1:Known structure; 2:Known regiochemistry; 3:Partial structure; 4:Sum-composition)

Table of KEGG reactions in human pathways involving Linoleic acid

Rxn IDKEGG ReactionEnzyme
R07055 Linoleate + Oxygen + NADPH + H+ <=> 9(10)-EpOME + NADP+ + H2OLinoleate + Oxygen + NADPH + H+ <=> 9(10)-EpOME + NADP+ + H2O
R07056 Linoleate + Oxygen + NADPH + H+ <=> 12(13)-EpOME + NADP+ + H2OLinoleate + Oxygen + NADPH + H+ <=> 12(13)-EpOME + NADP+ + H2O
R07064 Phosphatidylcholine + H2O <=> 1-Acyl-sn-glycero-3-phosphocholine + Linoleatephosphatidylcholine 2-acylhydrolase
R08177 Linoleoyl-CoA + H2O <=> CoA + LinoleateLinoleoyl-CoA hydrolase
R03626 Linoleate + Oxygen <=> (9Z,11E)-(13S)-13-Hydroperoxyoctadeca-9,11-dienoic acidLinoleate:oxygen 13-oxidoreductase

Table of KEGG human pathways containing Linoleic acid

Pathway IDHuman Pathway# of reactions
hsa00591 Linoleic acid metabolism 4
hsa01040 Biosynthesis of unsaturated fatty acids 1