RefMet Compound Details

MW structure37365 (View MW Metabolite Database details)
RefMet nameKynurenine
Systematic name(2S)-2-amino-4-(2-aminophenyl)-4-oxobutanoic acid
SMILESc1ccc(c(c1)C(=O)C[C@@H](C(=O)O)N)N   Run Tanimoto similarity search (with similarity coefficient >=0.6)
Exact mass208.084793 (neutral)
Calculate m/z:   
View other RefMet entries with this exact (neutral) mass:   +/- 0.05 amu   +/- 0.1 amu   +/- 0.2 amu   +/- 0.5 amu
FormulaC10H12N2O3View other entries in RefMet with this formula
InChIKeyYGPSJZOEDVAXAB-QMMMGPOBSA-NView other enantiomers/diastereomers of this metabolite in RefMet
Super ClassOrganic acids
Main ClassAmino acids and peptides
Sub ClassAmino acids
Pubchem CID161166
Annotation level1   (1:Known structure; 2:Known regiochemistry; 3:Partial structure; 4:Sum-composition)

Table of KEGG reactions in human pathways involving Kynurenine

Rxn IDKEGG ReactionEnzyme
R01960 L-Kynurenine + Oxygen + NADPH + H+ <=> 3-Hydroxy-L-kynurenine + NADP+ + H2OL-Kynurenine,NADPH:oxygen oxidoreductase (3-hydroxylating)
R00987 L-Kynurenine + H2O <=> Anthranilate + L-AlanineL-Kynurenine hydrolase
R01959 L-Formylkynurenine + H2O <=> Formate + L-KynurenineN-Formyl-L-kynurenine amidohydrolase
R01956 L-Kynurenine + 2-Oxoglutarate <=> 4-(2-Aminophenyl)-2,4-dioxobutanoate + L-GlutamateL-Kynurenine:2-oxoglutarate aminotransferase

Table of KEGG human pathways containing Kynurenine

Pathway IDHuman Pathway# of reactions
hsa00380 Tryptophan metabolism 4
hsa00630 Glyoxylate and dicarboxylate metabolism 1