RefMet Compound Details

MW structure41433 (View MW Metabolite Database details)
RefMet nameHydroxykynurenine
Systematic name(2S)-2-amino-4-(2-amino-3-hydroxyphenyl)-4-oxobutanoic acid
SMILESc1cc(C(=O)C[C@@H](C(=O)O)N)c(c(c1)O)N   Run Tanimoto similarity search (with similarity coefficient >=0.6)
Exact mass224.079708 (neutral)
Calculate m/z:   
View other RefMet entries with this exact (neutral) mass:   +/- 0.05 amu   +/- 0.1 amu   +/- 0.2 amu   +/- 0.5 amu
FormulaC10H12N2O4View other entries in RefMet with this formula
InChIKeyVCKPUUFAIGNJHC-LURJTMIESA-NView other enantiomers/diastereomers of this metabolite in RefMet
Super ClassOrganic acids
Main ClassAmino acids and peptides
Sub ClassAmino acids
Pubchem CID11811
Annotation level1   (1:Known structure; 2:Known regiochemistry; 3:Partial structure; 4:Sum-composition)

Table of KEGG reactions in human pathways involving Hydroxykynurenine

Rxn IDKEGG ReactionEnzyme
R01960 L-Kynurenine + Oxygen + NADPH + H+ <=> 3-Hydroxy-L-kynurenine + NADP+ + H2OL-Kynurenine,NADPH:oxygen oxidoreductase (3-hydroxylating)
R02668 3-Hydroxy-L-kynurenine + H2O <=> 3-Hydroxyanthranilate + L-Alanine3-Hydroxy-L-kynurenine hydrolase
R04171 3-Hydroxy-L-kynurenine + 2-Oxoglutarate <=> 4-(2-Amino-3-hydroxyphenyl)-2,4-dioxobutanoate + L-Glutamate3-Hydroxy-L-kynurenine:2-oxoglutarate aminotransferase

Table of KEGG human pathways containing Hydroxykynurenine

Pathway IDHuman Pathway# of reactions
hsa00380 Tryptophan metabolism 3