RefMet Compound Details

MW structure37700 (View MW Metabolite Database details)
RefMet nameGTP
Systematic name({[({[(2R,3S,4R,5R)-5-(2-amino-6-oxo-6,9-dihydro-1H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}(hydroxy)phosphoryl)oxy](hydroxy)phosphoryl}oxy)phosphonic acid
SMILESC([C@@H]1[C@H]([C@H]([C@H](n2cnc3c2nc(N)[nH]c3=O)O1)O)O)OP(=O)(O)OP(=O)(O)OP(=O)(O)O   Run Tanimoto similarity search (with similarity coefficient >=0.6)
Exact mass522.990669 (neutral)
Calculate m/z:   
View other RefMet entries with this exact (neutral) mass:   +/- 0.05 amu   +/- 0.1 amu   +/- 0.2 amu   +/- 0.5 amu
FormulaC10H16N5O14P3View other entries in RefMet with this formula
InChIKeyXKMLYUALXHKNFT-UUOKFMHZSA-NView other enantiomers/diastereomers of this metabolite in RefMet
Super ClassNucleic acids
Main ClassPurines
Sub ClassPurine rNTP
Pubchem CID135398633
Annotation level1   (1:Known structure; 2:Known regiochemistry; 3:Partial structure; 4:Sum-composition)

Table of KEGG reactions in human pathways involving GTP

Rxn IDKEGG ReactionEnzyme
R00428 GTP + H2O <=> Formamidopyrimidine nucleoside triphosphateGTP 8,9-hydrolase
R00434 GTP <=> 3',5'-Cyclic GMP + DiphosphateGTP diphosphate-lyase (cyclizing
R00330 ATP + GDP <=> ADP + GTPATP:GDP phosphotransferase
R00424 GTP + H2O <=> 7,8-Dihydroneopterin 3'-triphosphate + FormateGTP 7,8-8,9-dihydrolase
R00426 GTP + H2O <=> GMP + DiphosphateGTP diphosphohydrolase (diphosphate-forming)
R09394 GTP + S-Adenosyl-L-methionine + Reduced acceptor <=> (8S)-3',8-Cyclo-7,8-dihydroguanosine 5'-triphosphate + 5'-Deoxyadenosine + L-Methionine + AcceptorGTP 3',8-cyclase [(8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate-forming]
R00430 GTP + Pyruvate <=> GDP + PhosphoenolpyruvateGTP:pyruvate 2-O-phosphotransferase
R00335 GTP + H2O <=> GDP + OrthophosphateGTP phosphohydrolase
R01232 P1,P4-Bis(5'-guanosyl) tetraphosphate + H2O <=> GTP + GMPP1,P4-bis(5'-guanosyl)-tetraphosphate guanylylhydrolase

Table of KEGG human pathways containing GTP

Pathway IDHuman Pathway# of reactions
hsa00230 Purine metabolism 6
hsa00790 Folate biosynthesis 2
hsa01240 Biosynthesis of cofactors 1