RefMet Compound Details

RefMet ID, RefMet name, exact mass and formula
RefMet IDRM0135892
RefMet nameFormic acid
Systematic nameformic acid
SynonymsPubChem Synonyms
Exact mass46.005480 (neutral)
Calculate m/z:   
View other RefMet entries with this exact (neutral) mass:   +/- 0.05 amu   +/- 0.1 amu   +/- 0.2 amu   +/- 0.5 amu
FormulaCH2O2View other entries in RefMet with this formula
Molecular descriptors
Molfile37099 (Download molfile/View MW Metabolite Database details)
InChIInChI=1S/CH2O2/c2-1-3/h1H,(H,2,3)
InChIKeyBDAGIHXWWSANSR-UHFFFAOYSA-NView other enantiomers/diastereomers of this metabolite in RefMet
SMILESC(=O)O
Run Tanimoto similarity search (with similarity coefficient >=0.6)
Chemical/Biochemical Classification
Super ClassOrganic acids
Main ClassCarboxylic acids
Sub ClassCarboxylic acids
Distribution of Formic acid in NMDR studies
SpeciesPlot Species distribution
Sample sourcePlot Sample source(tissue) distribution
PlatformPlatform (MS/NMR) used for detection
ChromatographyChromatography methods used for detection
StudiesNMDR Studies reporting Formic acid
External Links
Pubchem CID284
ChEBI ID30751
KEGG IDC00058
HMDB IDHMDB0000142
Chemspider ID278
MetaCyc IDFORMATE
EPA CompToxDTXCID904115
Spectral data for Formic acid standards
BMRB ID(NMR)View NMR spectra
NP-MRD ID(NMR)View NMR spectra
Structural annotation level
Annotation level1   (1:Known structure; 2:Known regiochemistry; 3:Partial structure; 4:Sum-composition)

Table of KEGG reactions in human pathways involving Formic acid

Rxn IDKEGG ReactionEnzyme
R00527 S-Formylglutathione + H2O <=> Formate + GlutathioneS-Formylglutathione hydrolase
R00604 Formaldehyde + NAD+ + H2O <=> Formate + NADH + H+Formaldehyde:NAD+ oxidoreductase
R00614 2 Formaldehyde + H2O <=> Formate + Methanolformaldehyde:formaldehyde oxidoreductase
R00943 Tetrahydrofolate + Formate + ATP <=> ADP + Orthophosphate + 10-FormyltetrahydrofolateFormate:tetrahydrofolate ligase (ADP-forming)
R01959 L-Formylkynurenine + H2O <=> Formate + L-KynurenineN-Formyl-L-kynurenine amidohydrolase
R06982 Glutathione + Formaldehyde <=> S-(Hydroxymethyl)glutathioneS-(hydroxymethyl)glutathione formaldehyde-lyase (glutathione-forming)
R06983 S-(Hydroxymethyl)glutathione + NAD+ <=> S-Formylglutathione + NADH + H+S-(hydroxymethyl)glutathione dehydrogenase

Table of KEGG human pathways containing Formic acid

Pathway IDHuman Pathway# of reactions
hsa01200 Carbon metabolism 4
hsa00670 One carbon pool by folate 1
hsa01100 Metabolic pathways 1
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