RefMet Compound Details

MW structure37083 (View MW Metabolite Database details)
RefMet nameFolic acid
Systematic name(2S)-2-[(4-{[(2-amino-4-oxo-1,4-dihydropteridin-6-yl)methyl]amino}phenyl)formamido]pentanedioic acid
SMILESc1cc(ccc1C(=O)N[C@@H](CCC(=O)O)C(=O)O)NCc1cnc2c(c(=O)[nH]c(N)n2)n1   Run Tanimoto similarity search (with similarity coefficient >=0.6)
Exact mass441.139683 (neutral)
Calculate m/z:   
View other RefMet entries with this exact (neutral) mass:   +/- 0.05 amu   +/- 0.1 amu   +/- 0.2 amu   +/- 0.5 amu
FormulaC19H19N7O6View other entries in RefMet with this formula
InChIKeyOVBPIULPVIDEAO-LBPRGKRZSA-NView other enantiomers/diastereomers of this metabolite in RefMet
Super ClassOrganoheterocyclic compounds
Main ClassPterins
Sub ClassFolic acids
Pubchem CID135398658
Annotation level1   (1:Known structure; 2:Known regiochemistry; 3:Partial structure; 4:Sum-composition)

Table of KEGG reactions in human pathways involving Folic acid

Rxn IDKEGG ReactionEnzyme
R00937 Tetrahydrofolate + 2 NAD+ <=> Folate + 2 NADH + 2 H+5,6,7,8-tetrahydrofolate:NAD+ oxidoreductase
R00940 Tetrahydrofolate + 2 NADP+ <=> Folate + 2 NADPH + 2 H+5,6,7,8-tetrahydrofolate:NADP+ oxidoreductase
R02236 Dihydrofolate + NADP+ <=> Folate + NADPH + H+dihydrofolate:NADP+ oxidoreductase
R02235 Dihydrofolate + NAD+ <=> Folate + NADH + H+dihydrofolate:NAD+ oxidoreductase

Table of KEGG human pathways containing Folic acid

Pathway IDHuman Pathway# of reactions
hsa00670 One carbon pool by folate 4
hsa00790 Folate biosynthesis 4
hsa01100 Metabolic pathways 4
hsa01240 Biosynthesis of cofactors 4