RefMet Compound Details

MW structure37070 (View MW Metabolite Database details)
RefMet nameDimethylglycine
Systematic name2-(dimethylamino)acetic acid
SMILESCN(C)CC(=O)O   Run Tanimoto similarity search (with similarity coefficient >=0.6)
Exact mass103.063329 (neutral)
Calculate m/z:   
View other RefMet entries with this exact (neutral) mass:   +/- 0.05 amu   +/- 0.1 amu   +/- 0.2 amu   +/- 0.5 amu
FormulaC4H9NO2View other entries in RefMet with this formula
InChIKeyFFDGPVCHZBVARC-UHFFFAOYSA-NView other enantiomers/diastereomers of this metabolite in RefMet
Super ClassOrganic acids
Main ClassAmino acids and peptides
Sub ClassAmino acids
Pubchem CID673
Annotation level1   (1:Known structure; 2:Known regiochemistry; 3:Partial structure; 4:Sum-composition)

Table of KEGG reactions in human pathways involving Dimethylglycine

Rxn IDKEGG ReactionEnzyme
R01564 N,N-Dimethylglycine + H2O + Oxygen <=> Sarcosine + Formaldehyde + Hydrogen peroxideN,N-Dimethylglycine:oxygen oxidoreductase (demethylating)
R01565 N,N-Dimethylglycine + Tetrahydrofolate + Electron-transferring flavoprotein <=> Sarcosine + 5,10-Methylenetetrahydrofolate + Reduced electron-transferring flavoproteinN,N-dimethylglycine,5,6,7,8-tetrahydrofolate:electron-transferflavoprotein oxidoreductase (demethylating,5,10-methylenetetrahydrofolate-forming)
R02821 Betaine + L-Homocysteine <=> N,N-Dimethylglycine + L-MethionineTrimethylaminoacetate:L-homosysteine S-methyltransferase
R12787 Betaine + Co(I) corrinoid protein <=> N,N-Dimethylglycine + Methyl-Co(III) corrinoid proteinglycine betaine:[Co(I) glycine betaine-specific corrinoid protein] Co-methyltransferase
R13016 Betaine + NADH + H+ + Oxygen <=> N,N-Dimethylglycine + NAD+ + Formaldehyde + H2Oglycine betaine,NADH:oxygen oxidoreductase (demethylating)
R07244 S-Adenosyl-L-methionine + N,N-Dimethylglycine <=> S-Adenosyl-L-homocysteine + BetaineS-adenosyl-L-methionine:N,N-dimethylglycine N-methyltransferase
R13028 N,N-Dimethylglycine + 2 Oxidized ferredoxin + H2O <=> Sarcosine + Formaldehyde + 2 Reduced ferredoxin + 2 H+N,N-dimethylglycine:ferredoxin oxidoreductase (demethylating)

Table of KEGG human pathways containing Dimethylglycine

Pathway IDHuman Pathway# of reactions
hsa01100 Metabolic pathways 5
hsa00260 Glycine, serine and threonine metabolism 2
hsa00270 Cysteine and methionine metabolism 1