RefMet Compound Details
RefMet ID | RM0170613 | |
---|---|---|
MW structure | 50200 (View MW Metabolite Database details) | |
RefMet name | 5-Methyl-THF Species distribution Sample source distribution | |
Alternative name | 5-Methyltetrahydrofolic acid | |
Systematic name | N-[4-({[(6S)-2-amino-5-methyl-4-oxo-3,4,5,6,7,8-hexahydropteridin-6-yl]methyl}amino)benzoyl]-L-glutamic acid | |
SMILES | CN1[C@@H](CNc2ccc(cc2)C(=O)N[C@@H](CCC(=O)O)C(=O)O)CNc2c1c(=O)[nH]c(N)n2 Run Tanimoto similarity search (with similarity coefficient >=0.6) | |
Exact mass | 459.186632 (neutral) |
Table of KEGG reactions in human pathways involving 5-Methyl-THF
Rxn ID | KEGG Reaction | Enzyme |
---|---|---|
R00946 | 5-Methyltetrahydrofolate + L-Homocysteine <=> Tetrahydrofolate + L-Methionine | 5-Methyltetrahydrofolate:L-homocysteine S-methyltransferase |
R01217 | 5,10-Methylenetetrahydrofolate + 2 Reduced ferredoxin + 2 H+ <=> 5-Methyltetrahydrofolate + 2 Oxidized ferredoxin | 5-methyltetrahydrofolate:ferredoxin oxidoreductase |
R01224 | 5-Methyltetrahydrofolate + NADP+ <=> 5,10-Methylenetetrahydrofolate + NADPH + H+ | 5-methyltetrahydrofolate:NADP+ oxidoreductase |
R02289 | 5-Methyltetrahydrofolate + Co(I) corrinoid protein + H+ <=> Methyl-Co(III) corrinoid protein + Tetrahydrofolate | 5-methyltetrahydrofolate:corrinoid/iron-sulfur protein methyltransferase; |
R07168 | 5-Methyltetrahydrofolate + NAD+ <=> 5,10-Methylenetetrahydrofolate + NADH + H+ | 5-methyltetrahydrofolate:NAD+ oxidoreductase |
Table of KEGG human pathways containing 5-Methyl-THF
Pathway ID | Human Pathway | # of reactions |
---|---|---|
hsa01100 | Metabolic pathways | 3 |
hsa00670 | One carbon pool by folate | 1 |
hsa01200 | Carbon metabolism | 1 |