RefMet Compound Details

MW structure54272 (View MW Metabolite Database details)
RefMet name4,5-Dihydroorotic acid
Systematic name2,6-dioxo-1,3-diazinane-4-carboxylic acid
SMILESOC(=O)[C@@H]1CC(=O)NC(=O)N1
Exact mass158.032758 (neutral)
Calculate m/z:   
View other RefMet entries with this exact (neutral) mass:   +/- 0.05 amu   +/- 0.1 amu   +/- 0.2 amu   +/- 0.5 amu
FormulaC5H6N2O4View other entries in RefMet with this formula
InChIInChI=1S/C5H6N2O4/c8-3-1-2(4(9)10)6-5(11)7-3/h2H,1H2,(H,9,10)(H2,6,7,8,11)/t2-/m1/s1
InChIKeyUFIVEPVSAGBUSI-UWTATZPHSA-NView other enantiomers/diastereomers of this metabolite in RefMet
Super ClassOrganic acids
Main ClassAmino acids and peptides
Sub ClassAmino acids
Pubchem CID1149667
Annotation level1   (1:Known structure; 2:Known regiochemistry; 3:Partial structure; 4:Sum-composition)

Table of KEGG reactions in human pathways involving 4,5-Dihydroorotic acid

Rxn IDKEGG ReactionEnzyme
R01867 (S)-Dihydroorotate + Fumarate <=> Orotate + Succinate(S)-dihydroorotate:fumarate oxidoreductase
R01868 (S)-Dihydroorotate + Quinone <=> Orotate + Hydroquinone(S)-dihydroorotate:quinone oxidoreductase
R01869 (S)-Dihydroorotate + NAD+ <=> Orotate + H+ + NADH(S)-dihydroorotate:NAD+ oxidoreductase
R01993 (S)-Dihydroorotate + H2O <=> N-Carbamoyl-L-aspartate(S)-dihydroorotate amidohydrolase

Table of KEGG human pathways containing 4,5-Dihydroorotic acid

Pathway IDHuman Pathway# of reactions
hsa00240 Pyrimidine metabolism 2
hsa01100 Metabolic pathways 2
hsa01240 Biosynthesis of cofactors 2
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