List of human metabolic pathways and metabolites (REACTOME)

Pathway name (# of metabolites detected in study)Reactome pathway
Abnormal conversion of 2-oxoglutarate to 2-hydroxyglutarate REACT_160183
Aflatoxin activation and detoxification REACT_228214
alpha-linolenic acid (ALA) metabolism REACT_121147
Amino acid synthesis and interconversion (transamination) REACT_238
Androgen biosynthesis REACT_11059
Aromatic amines can be N-hydroxylated or N-dealkylated by CYP1A2 REACT_13721
Cell redox homeostasis REACT_121394
Cholesterol biosynthesis REACT_9405
Citric acid cycle (TCA cycle) REACT_1785
Cobalamin (Cbl, vitamin B12) transport and metabolism REACT_163862
Cross-presentation of particulate exogenous antigens (phagosomes) REACT_111174
CYP2E1 reactions REACT_13797
Cytosolic iron-sulfur cluster assembly REACT_160176
Defective MMACHC causes methylmalonic aciduria and homocystinuria type cblC REACT_169169
Defective MTRR causes methylmalonic aciduria and homocystinuria type cblE REACT_169439
Detoxification of Reactive Oxygen Species REACT_172715
Eicosanoids REACT_13645
Electron transport from NADPH to Ferredoxin REACT_150128
Endogenous sterols REACT_13812
eNOS activation REACT_12477
Estrogen biosynthesis REACT_11037
Fatty acids REACT_13814
Fatty Acyl-CoA Biosynthesis REACT_1319
FMO oxidises nucleophiles REACT_13653
Glucocorticoid biosynthesis REACT_11036
Glyoxylate metabolism REACT_16925
Heme degradation REACT_22297
Iron uptake and transport REACT_25060
Linoleic acid (LA) metabolism REACT_121100
Lysine catabolism REACT_1298
Metabolism of folate and pterines REACT_11167
Methylation REACT_6946
Mineralocorticoid biosynthesis REACT_11047
Miscellaneous substrates REACT_13425
Mtb iron assimilation by chelation REACT_121118
NADPH regeneration REACT_16904
Nitric oxide stimulates guanylate cyclase REACT_23862
Orphan transporters REACT_267716
Pentose phosphate pathway (hexose monophosphate shunt) REACT_1859
Phagosomal maturation (early endosomal stage) REACT_121256
Plasmalogen biosynthesis REACT_1407
Pregnenolone biosynthesis REACT_11038
Purine catabolism REACT_2086
Purine salvage REACT_1923
Pyrimidine catabolism REACT_1023
Regulation of thyroid hormone activity REACT_15297
Retinoid cycle disease events REACT_160130
Retinoid metabolism and transport REACT_24968
Sphingolipid de novo biosynthesis REACT_115810
Sterols are 12-hydroxylated by CYP8B1 REACT_13438
Synthesis and interconversion of nucleotide di- and triphosphates REACT_21330
Synthesis of 15-eicosatetraenoic acid derivatives REACT_150422
Synthesis of (16-20)-hydroxyeicosatetraenoic acids (HETE) REACT_150134
Synthesis of 5-eicosatetraenoic acids REACT_150209
Synthesis of bile acids and bile salts REACT_11054
Synthesis of bile acids and bile salts via 24-hydroxycholesterol REACT_11053
Synthesis of bile acids and bile salts via 27-hydroxycholesterol REACT_11048
Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol REACT_11041
Synthesis of Dolichyl-phosphate REACT_22230
Synthesis of epoxy (EET) and dihydroxyeicosatrienoic acids (DHET) REACT_150417
Synthesis of Leukotrienes (LT) and Eoxins (EX) REACT_150420
Synthesis of Lipoxins (LX) REACT_150320
Synthesis of Prostaglandins (PG) and Thromboxanes (TX) REACT_150149
Synthesis of very long-chain fatty acyl-CoAs REACT_380
Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation REACT_111176
The canonical retinoid cycle in rods (twilight vision) REACT_160156
The retinoid cycle in cones (daylight vision) REACT_160083
Thyroxine biosynthesis REACT_15292
Tryptophan catabolism REACT_916
Ubiquinol biosynthesis REACT_160111
VEGFA-VEGFR2 Pathway REACT_228166
VEGFR2 mediated vascular permeability REACT_228016
Vitamin D (calciferol) metabolism REACT_13523
Vitamins REACT_13450
Xenobiotics REACT_13543