Summary of Study ST001614

This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR001037. The data can be accessed directly via it's Project DOI: 10.21228/M8NM4H This work is supported by NIH grant, U2C- DK119886.

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Study IDST001614
Study TitleNMR metabolomics analysis of ricin-induced and fasting hypoglycemia (part-I)
Study TypeTargeted NMR
Study SummaryMice were subject to ricin exposure or fasting conditions for 2 hours, 8 hours, or an overnight time period. Following treatment, livers were removed and metabolites were extracted and analyzed by NMR.
Institute
Montana State University
DepartmentChemistry & Biochemistry
LaboratoryCopié
Last NameKempa
First NameJake
Address103 Chemistry and Biochemistry Building
Emailjkempa97@gmail.com
Phone4067997200
Submit Date2020-09-23
Num Groups9
Total Subjects107
Num Males54
Num Females53
Raw Data AvailableYes
Raw Data File Type(s)d
Analysis Type DetailNMR
Release Date2022-11-29
Release Version1
Jake Kempa Jake Kempa
https://dx.doi.org/10.21228/M8NM4H
ftp://www.metabolomicsworkbench.org/Studies/ application/zip

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Treatment:

Treatment ID:TR001704
Treatment Summary:Mice were injected via intraperitoneal (IP) route with either ricin or saline in 10 µL per g body weight. Mice in all but the fasted group were given food and water ad libitum. Fasted mice were transferred to new cages with fresh bedding where they had food withheld while given water ad libitum. Mice were sacrificed at 2hr (ricin), 8 hr (ricin and fasted), and overnight (16-22 hr, control, ricin, fasted).
Treatment Route:Intraperitoneal
Treatment Dose:0.6 µg/kg body weight or 30 µg/kg body weight
Treatment Vehicle:saline
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