Summary of Study ST001213
This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR000811. The data can be accessed directly via it's Project DOI: 10.21228/M8VD62 This work is supported by NIH grant, U2C- DK119886. See: https://www.metabolomicsworkbench.org/about/howtocite.php
| Study ID | ST001213 |
| Study Title | Serum lipidomic profile of cold-exposed Ucp1cre/12-LOX KO mice |
| Study Summary | We aimed to evaluate whether specific deletion of 12-Lipoxygenase (12-LOX) in brown fat can affect the serum concentrations of 12-LOX products under cold exposure. |
| Institute | Joslin Diabetes Center |
| Last Name | Leiria |
| First Name | Luiz |
| Address | One Joslin Place, 02215, Boston, MA-USA |
| luiz.leiria@joslin.harvard.edu | |
| Phone | 617-309-1967 |
| Submit Date | 2019-06-26 |
| Raw Data Available | Yes |
| Raw Data File Type(s) | wiff |
| Analysis Type Detail | LC-MS |
| Release Date | 2019-09-23 |
| Release Version | 1 |
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Treatment:
| Treatment ID: | TR001295 |
| Treatment Summary: | Wild-type and Ucp1CRE/12-LOX KO mice were exposed to a short-term cold temperature (1 hour at 5C) or kept at room temperature. After this period, the serum was collected as described. Ucp1CRE/12-LOX KO mice were created through CRISPR-Cas9 technology, as described in Leiria et al., 2019, Cell Metabolism. |