Summary of Study ST000587

This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench,, where it has been assigned Project ID PR000430. The data can be accessed directly via it's Project DOI: 10.21228/M8GC82 This work is supported by NIH grant, U2C- DK119886.


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Study IDST000587
Study TitleMetabolomics of Exhaled Breath Condensate in Decompensated Heart Failure
Study SummaryThe aim of the study was to test weather characteristic differences or changes in metabolic profile exist between exhaled breath condensate (EBC) and saliva of healthy individuals and heart failure patients. EBC NMR profiling was performed.
Mayo Clinic
DepartmentCardiovascular Diseases
LaboratoryMayo Metabolomics Core
Last NameJohnson
First NameBruce
Address200 First Street SW, Rochester, MN 55905
Submit Date2017-04-07
Analysis Type DetailNMR
Release Date2019-05-15
Release Version1
Bruce Johnson Bruce Johnson application/zip

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Treatment ID:TR000624
Treatment Summary:We will focus initially on patients with classic systolic HF who are admitted to St Mary’s Hospital with decompensated disease. These patients are currently being studied to quantify changes in lung water during the “recompensation” diuresis in the hospital and the related changes in alveolar gas conductance and breathing pattern to develop a predictive algorithm for likelihood of readmission, but also to obtain a better understanding of fluid regulation in the lungs. As these subjects are recruited, we will recruit age and sex matched stable HF patients going through similar testing in parallel running studies as well as age and sex matched control subjects. We will target 12 subjects per group and in addition to the EBC collection we will obtain saliva samples and blood at the same time points.