Summary of Study ST002349
This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR001509. The data can be accessed directly via it's Project DOI: 10.21228/M8N71K This work is supported by NIH grant, U2C- DK119886.
See: https://www.metabolomicsworkbench.org/about/howtocite.php
This study contains a large results data set and is not available in the mwTab file. It is only available for download via FTP as data file(s) here.
Study ID | ST002349 |
Study Title | Biomolecular condensates create phospholipid-enriched microenvironments (Part 1) |
Study Type | Metabolomes of in vitro synthesized condensates |
Study Summary | Proteins and RNA are able to phase separate from the aqueous cellular environment to form sub-cellular compartments called condensates. This process results in a protein-RNA mixture that is chemically distinct from the surrounding aqueous phase. Here we use mass spectrometry to characterize the metabolomes of condensates. To test this, we prepared mixtures of phase-separated proteins and cellular metabolites and identified metabolites enriched in the condensate phase. These proteins included SARS-CoV-2 nucleocapsid, as well as low complexity domains of MED1 and HNRNPA1. |
Institute | Cornell University |
Department | Department of Pharmacology |
Laboratory | Dr. Samie Jaffrey |
Last Name | Dumelie |
First Name | Jason |
Address | 1300 York Ave, LC-524, New York City, NY |
jdumes98@gmail.com | |
Phone | 6465690174 |
Submit Date | 2022-11-04 |
Raw Data Available | Yes |
Raw Data File Type(s) | mzdata.xml |
Analysis Type Detail | Other |
Release Date | 2023-03-01 |
Release Version | 2 |
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Subject:
Subject ID: | SU002591 |
Subject Type: | Mammal |
Subject Species: | Mus musculus |
Taxonomy ID: | 10090 |