Summary of Study ST001467

This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench,, where it has been assigned Project ID PR000999. The data can be accessed directly via it's Project DOI: 10.21228/M8K10H This work is supported by NIH grant, U2C- DK119886.


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Study IDST001467
Study TitleMetabolites changes related to glucose-mediated energy production in chemotheraphy-induced cachexia
Study SummaryTargeted metabolomics platforms included amino acids and metabolites related to glucose-mediated energy production. The targeted metabolome changed with chemotheraphy-induced cachexia, and the changes were reversed with potential treatment of the cachexia. .rdb files were included as raw data files where detailed information regarding MRM transitions and internal standards can be found. Several amino acids (Gly, Pro, Gln, Taurine) were analyzed after dilution because their peak intensities were too high. Thus their analysis was performed separately from other amino acids, and their rdb files were saved in separate rdb files.
Asan Medical Center; University of Ulsan
Last NameYoo
First NameHyun Ju
Address88, Olympic-ro, 43-gil, Songpa-gu, Seoul 05505, South Korea
Submit Date2020-08-18
Raw Data AvailableYes
Analysis Type DetailLC-MS
Release Date2020-09-21
Release Version1
Hyun Ju Yoo Hyun Ju Yoo application/zip

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Sample Preparation:

Sampleprep ID:SP001549
Sampleprep Summary:Metabolites related to glucose-mediated energy metabolism were extracted using LLE. Amino acids and bioamines were also extracted using LLE and underwent chemical derivatization with phenylisothiocyante.
Processing Storage Conditions:4℃
Extraction Method:Liquid Liquid Extraction (LLE)