Summary of Study ST001295

This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench,, where it has been assigned Project ID PR000876. The data can be accessed directly via it's Project DOI: 10.21228/M8FX1M This work is supported by NIH grant, U2C- DK119886.


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Study IDST001295
Study TitleEstimating Platelet Mitochondrial Function in Patients with Sepsis - WB NMRs (part-II)
Study Typesingle timepoint
Study SummaryRelationships between platelet mitochondrial oxygen consumption rates (mOCR) and metabolites in platelets as measured by quantitative 1H-NMR metabolomics in WB. Comparison of mitochondrial function and metabolomics in patients with sepsis and non-sepsis ED patients
University of Michigan; University of Mississippi; University of Minnesota
DepartmentClinical Pharmacy (UMich); Emergency Medicine (UMiss)
LaboratoryStringer NMR Metabolomics Laboratory
Last NameMcHugh
First NameCora
Address428 Church St, Ann Arbor, MI, 48103, USA
Submit Date2019-12-13
Num Groups2
Total Subjects26
Num Males14
Num Females12
Raw Data AvailableYes
Raw Data File Type(s)fid
Analysis Type DetailNMR
Release Date2020-05-26
Release Version1
Cora McHugh Cora McHugh application/zip

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Project ID:PR000876
Project DOI:doi: 10.21228/M8FX1M
Project Title:Estimating Platelet Mitochondrial Function in Patients with Sepsis
Project Type:Quantitative NMR Metabolomics
Project Summary:Sepsis patients and ill controls admitted to the ED had matched whole blood (WB) and isolated platelet samples collected. The control group was chosen to represent an acutely ill 127cohort of the same racial, sex, and age as the sepsis cohort. NMR was run on extracted WB and platelets to determine how the metabolome reflects mitochondrial function
Institute:University of Michigan; University of Mississippi; University of Minnesota
Department:Clinical Pharmacy (UMich); Emergency Medicine (UMiss)
Laboratory:Stringer NMR Metabolomics Laboratory
Last Name:McHugh
First Name:Cora
Address:428 Church St, Ann Arbor, MI, 48103, USA
Funding Source:GM111400, K23GM113041
Contributors:Kathleen Stringer, Mike Puskarich, Marc McCann