Summary of Study ST001295
This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR000876. The data can be accessed directly via it's Project DOI: 10.21228/M8FX1M This work is supported by NIH grant, U2C- DK119886.
See: https://www.metabolomicsworkbench.org/about/howtocite.php
| Study ID | ST001295 |
| Study Title | Estimating Platelet Mitochondrial Function in Patients with Sepsis - WB NMRs (part-II) |
| Study Type | single timepoint |
| Study Summary | Relationships between platelet mitochondrial oxygen consumption rates (mOCR) and metabolites in platelets as measured by quantitative 1H-NMR metabolomics in WB. Comparison of mitochondrial function and metabolomics in patients with sepsis and non-sepsis ED patients |
| Institute | University of Michigan; University of Mississippi; University of Minnesota |
| Department | Clinical Pharmacy (UMich); Emergency Medicine (UMiss) |
| Laboratory | Stringer NMR Metabolomics Laboratory |
| Last Name | McHugh |
| First Name | Cora |
| Address | 428 Church St, Ann Arbor, MI, 48103, USA |
| NMRmetabolomics@umich.edu | |
| Phone | 7343530164 |
| Submit Date | 2019-12-13 |
| Num Groups | 2 |
| Total Subjects | 26 |
| Num Males | 14 |
| Num Females | 12 |
| Raw Data Available | Yes |
| Raw Data File Type(s) | fid |
| Analysis Type Detail | NMR |
| Release Date | 2020-05-26 |
| Release Version | 1 |
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Project:
| Project ID: | PR000876 |
| Project DOI: | doi: 10.21228/M8FX1M |
| Project Title: | Estimating Platelet Mitochondrial Function in Patients with Sepsis |
| Project Type: | Quantitative NMR Metabolomics |
| Project Summary: | Sepsis patients and ill controls admitted to the ED had matched whole blood (WB) and isolated platelet samples collected. The control group was chosen to represent an acutely ill 127cohort of the same racial, sex, and age as the sepsis cohort. NMR was run on extracted WB and platelets to determine how the metabolome reflects mitochondrial function |
| Institute: | University of Michigan; University of Mississippi; University of Minnesota |
| Department: | Clinical Pharmacy (UMich); Emergency Medicine (UMiss) |
| Laboratory: | Stringer NMR Metabolomics Laboratory |
| Last Name: | McHugh |
| First Name: | Cora |
| Address: | 428 Church St, Ann Arbor, MI, 48103, USA |
| Email: | NMRmetabolomics@umich.edu |
| Phone: | 7343530164 |
| Funding Source: | GM111400, K23GM113041 |
| Contributors: | Kathleen Stringer, Mike Puskarich, Marc McCann |
