Summary of Study ST003520

This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR002165. The data can be accessed directly via it's Project DOI: 10.21228/M8S247 This work is supported by NIH grant, U2C- DK119886. See: https://www.metabolomicsworkbench.org/about/howtocite.php

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Study IDST003520
Study TitleIdentification of Plasma Metabolomic Biomarkers of Juvenile Idiopathic Arthritis
Study TypeClinical
Study SummaryThis study utilizes plasma metabolomic profiling to identify biomarkers associated with juvenile idiopathic arthritis (JIA) by analyzing samples from treatment-naïve JIA patients and non-JIA controls. Significant metabolic alterations were detected, with sphingosine metabolites and fatty acid ethanolamides showing notable increases in JIA patients, while specific compounds such as sarcosine were decreased. The research highlights 11 highly discriminatory metabolites, including sphinganine-1-phosphate, demonstrating potential for improved JIA diagnosis and treatment through targeted metabolic profiling.
Institute
University of Kansas
DepartmentCenter for Computational Biology
LaboratoryFunk
Last NameKumar
First NameAmar
AddressMultidisciplinary Research Bldg. 2030 Becker Drive Lawrence, KS 66047
Emailamarkumar@ku.edu
Phone18723016225
Submit Date2024-09-09
Num Groups2
Total Subjects210
Num Males82
Num Females128
Study CommentsAlthough the raw dataset initially included 210 subjects, only 207 were included in the final analysis due to consent-related exclusions. These three subjects were removed to ensure compliance with ethical standards.
Analysis Type DetailLC-MS
Release Date2024-11-01
Release Version1
Amar Kumar Amar Kumar
https://dx.doi.org/10.21228/M8S247
ftp://www.metabolomicsworkbench.org/Studies/ application/zip

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Factors:

Subject type: Human; Subject species: Homo sapiens (Factor headings shown in green)

mb_sample_id local_sample_id Group
SA386516UKAN-00680Crohn's Disease
SA386517UKAN-00636Crohn's Disease
SA386518UKAN-00637Crohn's Disease
SA386519UKAN-00642Crohn's Disease
SA386520UKAN-00643Crohn's Disease
SA386521UKAN-00645Crohn's Disease
SA386522UKAN-00670Crohn's Disease
SA386523UKAN-00671Crohn's Disease
SA386524UKAN-00674Crohn's Disease
SA386525UKAN-00675Crohn's Disease
SA386526UKAN-00677Crohn's Disease
SA386527UKAN-00683Crohn's Disease
SA386528UKAN-00633Crohn's Disease
SA386529UKAN-00684Crohn's Disease
SA386530UKAN-00686Crohn's Disease
SA386531UKAN-00710Crohn's Disease
SA386532UKAN-00714Crohn's Disease
SA386533UKAN-00715Crohn's Disease
SA386534UKAN-00716Crohn's Disease
SA386535UKAN-00721Crohn's Disease
SA386536UKAN-00723Crohn's Disease
SA386537UKAN-00724Crohn's Disease
SA386538UKAN-00725Crohn's Disease
SA386539UKAN-00635Crohn's Disease
SA386540UKAN-00712Crohn's Disease
SA386541UKAN-00631Crohn's Disease
SA386542UKAN-00632Healthy_Control
SA386543UKAN-00827Healthy_Control
SA386544UKAN-00708Healthy_Control
SA386545UKAN-00707Healthy_Control
SA386546UKAN-00822Healthy_Control
SA386547UKAN-00823Healthy_Control
SA386548UKAN-00824Healthy_Control
SA386549UKAN-00825Healthy_Control
SA386550UKAN-00826Healthy_Control
SA386551UKAN-00829Healthy_Control
SA386552UKAN-00828Healthy_Control
SA386553UKAN-00711Healthy_Control
SA386554UKAN-00830Healthy_Control
SA386555UKAN-00831Healthy_Control
SA386556UKAN-00832Healthy_Control
SA386557UKAN-00833Healthy_Control
SA386558UKAN-00685Healthy_Control
SA386559UKAN-00682Healthy_Control
SA386560UKAN-00681Healthy_Control
SA386561UKAN-00709Healthy_Control
SA386562UKAN-00717Healthy_Control
SA386563UKAN-00713Healthy_Control
SA386564UKAN-00801Healthy_Control
SA386565UKAN-00793Healthy_Control
SA386566UKAN-00794Healthy_Control
SA386567UKAN-00795Healthy_Control
SA386568UKAN-00796Healthy_Control
SA386569UKAN-00797Healthy_Control
SA386570UKAN-00798Healthy_Control
SA386571UKAN-00799Healthy_Control
SA386572UKAN-00800Healthy_Control
SA386573UKAN-00802Healthy_Control
SA386574UKAN-00678Healthy_Control
SA386575UKAN-00803Healthy_Control
SA386576UKAN-00804Healthy_Control
SA386577UKAN-00726Healthy_Control
SA386578UKAN-00634Healthy_Control
SA386579UKAN-00722Healthy_Control
SA386580UKAN-00720Healthy_Control
SA386581UKAN-00719Healthy_Control
SA386582UKAN-00718Healthy_Control
SA386583UKAN-00679Healthy_Control
SA386584UKAN-00834Healthy_Control
SA386585UKAN-00853Healthy_Control
SA386586UKAN-00864Healthy_Control
SA386587UKAN-00854Healthy_Control
SA386588UKAN-00676Healthy_Control
SA386589UKAN-00852Healthy_Control
SA386590UKAN-00856Healthy_Control
SA386591UKAN-00857Healthy_Control
SA386592UKAN-00858Healthy_Control
SA386593UKAN-00859Healthy_Control
SA386594UKAN-00860Healthy_Control
SA386595UKAN-00861Healthy_Control
SA386596UKAN-00862Healthy_Control
SA386597UKAN-00855Healthy_Control
SA386598UKAN-00646Healthy_Control
SA386599UKAN-00863Healthy_Control
SA386600UKAN-00667Healthy_Control
SA386601UKAN-00668Healthy_Control
SA386602UKAN-00630Healthy_Control
SA386603UKAN-00629Healthy_Control
SA386604UKAN-00638Healthy_Control
SA386605UKAN-00673Healthy_Control
SA386606UKAN-00639Healthy_Control
SA386607UKAN-00640Healthy_Control
SA386608UKAN-00672Healthy_Control
SA386609UKAN-00641Healthy_Control
SA386610UKAN-00628Healthy_Control
SA386611UKAN-00627Healthy_Control
SA386612UKAN-00644Healthy_Control
SA386613UKAN-00669Healthy_Control
SA386614UKAN-00808JIA
SA386615UKAN-00809JIA
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