Summary of Study ST003431

This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR001941. The data can be accessed directly via it's Project DOI: 10.21228/M8TM76 This work is supported by NIH grant, U2C- DK119886.

See: https://www.metabolomicsworkbench.org/about/howtocite.php

This study contains a large results data set and is not available in the mwTab file. It is only available for download via FTP as data file(s) here.

Study ID	ST003431
Study Title	Metabolomics analysis of breast cancer cell lines treated with dimethylmalonate (DMM), GSK2194069, and their combination.
Study Summary	Seven breast cancer cell lines (MDA-MB-468, SUM159PT, MCF7, HCC1806, MDA-MB-231, HS578T, CAL120) were treated with 5 mM DMM, 1 uM GSK2194069, and their combination, for 24 h. Intracellular samples were collected for the metabolomics analysis.
Institute	Wistar Institute
Department	Molecular and Cellular Oncogenesis Program, Ellen and Ronald Caplan Cancer Center
Laboratory	Schug's Lab
Last Name	Mukha
First Name	Dzmitry
Address	3601 Spruce St, Philadelphia, PA 19104, USA
Email	dmukha@wistar.org
Phone	+12154956903
Submit Date	2024-08-21
Num Groups	17
Total Subjects	51
Publications	Submission Pending
Raw Data Available	Yes
Raw Data File Type(s)	mzML, wiff
Analysis Type Detail	LC-MS
Release Date	2024-09-12
Release Version	1

Select appropriate tab below to view additional metadata details:

Factors:

Subject type: Cultured cells; Subject species: Homo sapiens (Factor headings shown in green)

mb_sample_id	local_sample_id	Sample source	Sample Type	Drug Treatment
SA377920	43 CAL120 GSK 1 uM	CAL120 breast cancer cells	Intracellular	1 uM GSK214069
SA377921	40 CAL120 GSK 1 uM	CAL120 breast cancer cells	Intracellular	1 uM GSK214069
SA377922	42 CAL120 DMM 5 mM	CAL120 breast cancer cells	Intracellular	5 mM dimethylmalonate
SA377923	39 CAL120 DMM 5 mM	CAL120 breast cancer cells	Intracellular	5 mM dimethylmalonate
SA377924	44 CAL120 Combination	CAL120 breast cancer cells	Intracellular	5 mM dimethylmalonate + 1 uM GSK214069
SA377925	41 CAL120 Combination	CAL120 breast cancer cells	Intracellular	5 mM dimethylmalonate + 1 uM GSK214069
SA377926	25 HCC1806 GSK 1 uM	HCC1806 breast cancer cells	Intracellular	1 uM GSK214069
SA377927	22 HCC1806 GSK 1 uM	HCC1806 breast cancer cells	Intracellular	1 uM GSK214069
SA377928	21 HCC1806 DMM 5 mM	HCC1806 breast cancer cells	Intracellular	5 mM dimethylmalonate
SA377929	24 HCC1806 DMM 5 mM	HCC1806 breast cancer cells	Intracellular	5 mM dimethylmalonate
SA377930	26 HCC1806 Combination	HCC1806 breast cancer cells	Intracellular	5 mM dimethylmalonate + 1 uM GSK214069
SA377931	23 HCC1806 Combination	HCC1806 breast cancer cells	Intracellular	5 mM dimethylmalonate + 1 uM GSK214069
SA377932	37 HS578T GSK 1 uM	HS578T breast cancer cells	Intracellular	1 uM GSK214069
SA377933	34 HS578T GSK 1 uM	HS578T breast cancer cells	Intracellular	1 uM GSK214069
SA377934	36 HS578T DMM 5 mM	HS578T breast cancer cells	Intracellular	5 mM dimethylmalonate
SA377935	33 HS578T DMM 5 mM	HS578T breast cancer cells	Intracellular	5 mM dimethylmalonate
SA377936	38 HS578T Combination	HS578T breast cancer cells	Intracellular	5 mM dimethylmalonate + 1 uM GSK214069
SA377937	35 HS578T Combination	HS578T breast cancer cells	Intracellular	5 mM dimethylmalonate + 1 uM GSK214069
SA377938	16 MCF7 GSK 1 uM	MCF7 breast cancer cells	Intracellular	1 uM GSK214069
SA377939	19 MCF7 GSK 1 uM	MCF7 breast cancer cells	Intracellular	1 uM GSK214069
SA377940	15 MCF7 DMM 5 mM	MCF7 breast cancer cells	Intracellular	5 mM dimethylmalonate
SA377941	18 MCF7 DMM 5 mM	MCF7 breast cancer cells	Intracellular	5 mM dimethylmalonate
SA377942	17 MCF7 Combination	MCF7 breast cancer cells	Intracellular	5 mM dimethylmalonate + 1 uM GSK214069
SA377943	20 MCF7 Combination	MCF7 breast cancer cells	Intracellular	5 mM dimethylmalonate + 1 uM GSK214069
SA377944	28 MDA-MB-231 GSK 1 uM	MDA-MB-231 breast cancer cells	Intracellular	1 uM GSK214069
SA377945	31 MDA-MB-231 GSK 1 uM	MDA-MB-231 breast cancer cells	Intracellular	1 uM GSK214069
SA377946	30 MDA-MB-231 DMM 5 mM	MDA-MB-231 breast cancer cells	Intracellular	5 mM dimethylmalonate
SA377947	27 MDA-MB-231 DMM 5 mM	MDA-MB-231 breast cancer cells	Intracellular	5 mM dimethylmalonate
SA377948	29 MDA-MB-231 Combination	MDA-MB-231 breast cancer cells	Intracellular	5 mM dimethylmalonate + 1 uM GSK214069
SA377949	32 MDA-MB-231 Combination	MDA-MB-231 breast cancer cells	Intracellular	5 mM dimethylmalonate + 1 uM GSK214069
SA377950	07 MDA-MB-468 GSK 1 uM	MDA-MB-468 breast cancer cells	Intracellular	1 uM GSK214069
SA377951	04 MDA-MB-468 GSK 1 uM	MDA-MB-468 breast cancer cells	Intracellular	1 uM GSK214069
SA377952	03 MDA-MB-468 DMM 5 mM	MDA-MB-468 breast cancer cells	Intracellular	5 mM dimethylmalonate
SA377953	06 MDA-MB-468 DMM 5 mM	MDA-MB-468 breast cancer cells	Intracellular	5 mM dimethylmalonate
SA377954	08 MDA-MB-468 Combination	MDA-MB-468 breast cancer cells	Intracellular	5 mM dimethylmalonate + 1 uM GSK214069
SA377955	05 MDA-MB-468 Combination	MDA-MB-468 breast cancer cells	Intracellular	5 mM dimethylmalonate + 1 uM GSK214069
SA377956	46 Blank	NA	Blank	NA
SA377957	01 Blank	NA	Blank	NA
SA377958	02 DMEM/F12 no adds	NA	QC	NA
SA377959	45 DMEM/F12 no adds	NA	QC	NA
SA377960	13 SUM159PT GSK 1 uM	SUM159PT breast cancer cells	Intracellular	1 uM GSK214069
SA377961	10 SUM159PT GSK 1 uM	SUM159PT breast cancer cells	Intracellular	1 uM GSK214069
SA377962	09 SUM159PT DMM 5 mM	SUM159PT breast cancer cells	Intracellular	5 mM dimethylmalonate
SA377963	12 SUM159PT DMM 5 mM	SUM159PT breast cancer cells	Intracellular	5 mM dimethylmalonate
SA377964	11 SUM159PT Combination	SUM159PT breast cancer cells	Intracellular	5 mM dimethylmalonate + 1 uM GSK214069
SA377965	14 SUM159PT Combination	SUM159PT breast cancer cells	Intracellular	5 mM dimethylmalonate + 1 uM GSK214069

Showing results 1 to 46 of 46

Showing results 1 to 46 of 46