Summary of Study ST001970

This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR001253. The data can be accessed directly via it's Project DOI: 10.21228/M8R98V This work is supported by NIH grant, U2C- DK119886.

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Study IDST001970
Study TitleAnalytical methodology for a metabolome atlas of goat’s plasma, milk and feces using 1H-NMR and UHPLC-HRMS:MS/milk
Study SummaryMetabolomics has been increasingly used in animal and food sciences. Animal health is one of the most important factors that can also alter animal integrity and welfare. Some studies have already investigated the link between health and metabolic profile of dairy animals. These studies in metabolomics often consider a single type of sample using a single analytical platform (Nuclear Magnetic Resonance or Mass Spectrometry). Only few studies with multi-platform approaches are also used with a single or a multi type of sample, but they mainly consider dairy cows metabolome although dairy goats present similar diseases, that it could be interesting to detect early to preserve animal health and milk production. This study aims to create a metabolic atlas of goat plasma, milk, and feces, based on healthy animals. Our study describes a Standard Operating Procedure for three goat matrices: blood plasma, milk, and feces using multiple platforms (NMR (1H), UHPLC (RP)-MS and UHPLC (HILIC)-MS) that follows a unique sample preparation procedure for each sample type to be analyzed on multi-platforms basis. Our method was evaluated for its robustness and allowed a better characterization of goat metabolic profile in healthy conditions.
Institute
INSERM
Last NameMartias
First NameCecile
Address10 Boulevard tonnelé, Tours, Indre et Loire, 37000, France
Emailcecile.martias@univ-tours.fr
Phone0247366351
Submit Date2021-09-27
Analysis Type DetailLC-MS
Release Date2022-01-02
Release Version1
Cecile Martias Cecile Martias
https://dx.doi.org/10.21228/M8R98V
ftp://www.metabolomicsworkbench.org/Studies/ application/zip

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Factors:

Subject type: Mammal; Subject species: Capra hircus (Factor headings shown in green)

mb_sample_id local_sample_id Protocole
SA185029L_200_P1_9P1
SA185030L_200_P1_10P1
SA185031L_200_P1_7P1
SA185032L_200_P1_1P1
SA185033L_200_P1_8P1
SA185034L_200_P1_6P1
SA185035L_200_P1_2P1
SA185036L_200_P1_4P1
SA185037L_200_P1_3P1
SA185038L_200_P1_5P1
SA185039L_200_P3_6P3
SA185040L_200_P3_7P3
SA185041L_200_P3_8P3
SA185042L_200_P3_9P3
SA185043L_200_P3_5P3
SA185044L_200_P3_4P3
SA185045L_200_P3_2P3
SA185046L_200_P3_1P3
SA185047L_200_P3_3P3
SA185048L_100_P4_8P4
SA185049L_100_P4_9P4
SA185050L_100_P4_10P4
SA185051L_100_P4_7P4
SA185052L_100_P4_4P4
SA185053L_100_P4_1P4
SA185054L_100_P4_2P4
SA185055L_100_P4_3P4
SA185056L_100_P4_5P4
SA185057L_100_P4_6P4
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