Summary of Study ST001127

This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR000754. The data can be accessed directly via it's Project DOI: 10.21228/M8709G This work is supported by NIH grant, U2C- DK119886.

See: https://www.metabolomicsworkbench.org/about/howtocite.php

This study contains a large results data set and is not available in the mwTab file. It is only available for download via FTP as data file(s) here.

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Study IDST001127
Study TitleLipid profiling of caecal samples from GF mice colonized with B. thetaiotaomicron WT or the ΔSPT mutants (part III)
Study SummaryTo study Bacteroidetes sphingolipids in intestinal health, we colonized germ-free mice with wild type or a sphingolipid-deficient Bacteroides thetaiotaomicron strain. A lack of Bacteroides derived sphingolipids increased intestinal inflammation, dysregulated innate immunity and altered the host ceramide pool.
Institute
Broad Institute of MIT and Harvard
Last NameAvila-Pacheco
First NameJulian
Address415 Main Street
Emailjravilap@broadinstitute.org
Phone617-714-8264
Submit Date2019-01-17
Num Groups3
Total Subjects14
Raw Data AvailableYes
Raw Data File Type(s)raw(Thermo)
Analysis Type DetailLC-MS
Release Date2019-03-06
Release Version1
Julian Avila-Pacheco Julian Avila-Pacheco
https://dx.doi.org/10.21228/M8709G
ftp://www.metabolomicsworkbench.org/Studies/ application/zip

Select appropriate tab below to view additional metadata details:

Factors:

Subject type: Mammal; Subject species: Mus musculus (Factor headings shown in green)

mb_sample_id local_sample_id Inoculum Strain
SA078054BTSPR Cecal_3Bacteroides thetaiotaomicron SPT K.O. (BT_0870)
SA078055BTSPR Cecal_4Bacteroides thetaiotaomicron SPT K.O. (BT_0870)
SA078056BTSPR Cecal_6Bacteroides thetaiotaomicron SPT K.O. (BT_0870)
SA078057BTSPR Cecal_1Bacteroides thetaiotaomicron SPT K.O. (BT_0870)
SA078058BTSPR Cecal_5Bacteroides thetaiotaomicron SPT K.O. (BT_0870)
SA078059BTSPR Cecal_2Bacteroides thetaiotaomicron SPT K.O. (BT_0870)
SA078060BTWT Cecal_3Bacteroides thetaiotaomicron WT (VPI-5482)
SA078061BTWT Cecal_2Bacteroides thetaiotaomicron WT (VPI-5482)
SA078062BTWT Cecal_1Bacteroides thetaiotaomicron WT (VPI-5482)
SA078063BTWT Cecal_4Bacteroides thetaiotaomicron WT (VPI-5482)
SA078064BTWT Cecal_5Bacteroides thetaiotaomicron WT (VPI-5482)
SA078065BTWT Cecal_6Bacteroides thetaiotaomicron WT (VPI-5482)
SA078066GF Cecal_1None None
SA078067GF Cecal_2None None
Showing results 1 to 14 of 14
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