Summary of Study ST000636

This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench,, where it has been assigned Project ID PR000457. The data can be accessed directly via it's Project DOI: 10.21228/M8060Z This work is supported by NIH grant, U2C- DK119886.


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Study IDST000636
Study TitleNeuromodulator Metabolites of Dietary Salt Effects on Blood Pressure in Human Urine from DASH2 Clinical Trial (part IX)
Study SummaryThe objective of the study is to identify changes of urinary metabolite profiles associated with different responses to blood pressure to salt. Subjects are derived from The Dietary approaches to stop hypertension (DASH) diet, Sodium Intake and Blood Pressure Trial (Sacks FM et al PMID: 11136953,N Engl J Med. 2001).We choose two groups subjects who meet the following conditions(the two groups are separately named A and B). We chose subjects on the Control diet .These subjects meet the blood pressure criteria described below:Group A subjects conditions: 1) On Control diet. 2) Normotensive subjects: systolic blood pressure from the low sodium visit is less than 140 and the diastolic blood pressure from low sodium visit is less than 90; 3) For group A: Either the systolic blood pressure from the high sodium visit was greater than 10 mmHg higher than the systolic blood pressure from the low sodium visit, or the diastolic blood pressure from the high sodium visit was greater than 10 mmHg higher than the diastolic blood pressure from the low sodium visit; 3) For group B: The systolic blood pressure from the high sodium visit is within 5 mmHg (i.e. +/- 5) from the systolic blood pressure from the low sodium visit, and the diastolic blood pressure from the high sodium visit is within 5 mmHg from the diastolic blood pressure from the low sodium visit. Use gas chromatography/mass spectrometry (GC/MS) analysis, and liquid chromatography/mass spectrometry (LC/MS)analysis to find the differences of metabolic profiles between the high sodium level and the low sodium level, and compare the metabolic profiles of A with the metabolic profiles of B at the low and high sodium level.
Mayo Clinic
Last NameLiang
First NameMingyu
AddressMedical College of Wisconsin 8701 Watertown Plank Road Milwaukee, WI 53226
Submit Date2017-06-23
Analysis Type DetailLC-MS
Release Date2019-07-17
Release Version1
Mingyu Liang Mingyu Liang application/zip

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Subject type: Human; Subject species: Homo sapiens (Factor headings shown in green)

mb_sample_id local_sample_id Sodium level grouping
SA035785ms5957-135H A
SA035786ms5957-156H A
SA035787ms5957-116H A
SA035788ms5957-56H A
SA035789ms5957-61H A
SA035790ms5957-44H A
SA035791ms5957-115H A
SA035792ms5957-157H A
SA035793ms5957-32H A
SA035794ms5957-31H A
SA035795ms5957-159H A
SA035796ms5957-37H A
SA035797ms5957-158H A
SA035798ms5957-62H A
SA035799ms5957-63H A
SA035800ms5957-86H A
SA035801ms5957-104H A
SA035802ms5957-90H A
SA035803ms5957-92H A
SA035804ms5957-98H A
SA035805ms5957-79H A
SA035806ms5957-107H A
SA035807ms5957-67H A
SA035808ms5957-113H A
SA035809ms5957-70H A
SA035810ms5957-71H A
SA035811ms5957-73H A
SA035812ms5957-160H A
SA035813ms5957-121H A
SA035814ms5957-11H A
SA035815ms5957-129H A
SA035816ms5957-18H A
SA035817ms5957-9H A
SA035818ms5957-8H A
SA035819ms5957-4H A
SA035820ms5957-131H A
SA035821ms5957-20H A
SA035822ms5957-15H A
SA035823ms5957-26H A
SA035824ms5957-25H A
SA035825ms5957-161H A
SA035826ms5957-164H B
SA035827ms5957-108H B
SA035828ms5957-74H B
SA035829ms5957-138H B
SA035830ms5957-163H B
SA035831ms5957-133H B
SA035832ms5957-40H B
SA035833ms5957-68H B
SA035834ms5957-123H B
SA035835ms5957-36H B
SA035836ms5957-124H B
SA035837ms5957-88H B
SA035838ms5957-166H B
SA035839ms5957-93H B
SA035840ms5957-134H B
SA035841ms5957-165H B
SA035842ms5957-103H B
SA035843ms5957-81H B
SA035844ms5957-27H B
SA035845ms5957-83H B
SA035846ms5957-144H B
SA035847ms5957-130H B
SA035848ms5957-13H B
SA035849ms5957-64H B
SA035850ms5957-118H B
SA035851ms5957-43H B
SA035852ms5957-117H B
SA035853ms5957-136H B
SA035854ms5957-50H B
SA035855ms5957-162H B
SA035856ms5957-127H B
SA035857ms5957-128H B
SA035858ms5957-45H B
SA035859ms5957-126H B
SA035860ms5957-41H B
SA035861ms5957-16H B
SA035862ms5957-125H B
SA035863ms5957-42H B
SA035864ms5957-60H B
SA035865ms5957-59H B
SA035866ms5957-58H B
SA035867ms5957-19H B
SA035868ms5957101L A
SA035869ms5957-100L A
SA035870ms5957-99L A
SA035871ms5957-105L A
SA035872ms5957-114L A
SA035873ms5957-112L A
SA035874ms5957-139L A
SA035875ms5957-106L A
SA035876ms5957-122L A
SA035877ms5957-97L A
SA035878ms5957-140L A
SA035879ms5957-66L A
SA035880ms5957-21L A
SA035881ms5957-52L A
SA035882ms5957-17L A
SA035883ms5957-14L A
SA035884ms5957-150L A
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