Summary of Study ST000546
This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR000400. The data can be accessed directly via it's Project DOI: 10.21228/M8BS4F This work is supported by NIH grant, U2C- DK119886.
See: https://www.metabolomicsworkbench.org/about/howtocite.php
| Study ID | ST000546 |
| Study Title | Multi-omics based identification of specific biochemical changes associated with PfKelch13-mutant artemisinin resistant Plasmodium |
| Study Type | Cell type comparison |
| Study Summary | Two clonaly artemisinin resistant parasitised red blood cells (trophozoite stage) were compared with artemsinin sensitive parasitised red blood cells by metabolomics analysis. |
| Institute | Monash University |
| Department | Monash Institute of Pharmaceutical Sciences, Drug Delivery, Disposition and Dynamics |
| Laboratory | Creek lab |
| Last Name | Creek |
| First Name | Darren |
| Address | 381 Royal Parade, Parkville, Melbourne, VIC3052, Australia |
| Darren.Creek@monash.edu | |
| Phone | N/A |
| Submit Date | 2017-01-23 |
| Num Groups | 4 |
| Total Subjects | 13 |
| Raw Data Available | Yes |
| Raw Data File Type(s) | raw(Thermo) |
| Analysis Type Detail | LC-MS |
| Release Date | 2017-07-10 |
| Release Version | 1 |
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Factors:
Subject type: Cells; Subject species: Plasmodium falciparum (Factor headings shown in green)
| mb_sample_id | local_sample_id | Artemisinin resistant | PfKelch13 mutation |
|---|---|---|---|
| SA028145 | R2_60exp3 | Resistant | C580Y |
| SA028146 | R2_60exp2 | Resistant | C580Y |
| SA028147 | R2_60exp1 | Resistant | C580Y |
| SA028148 | R1_60exp2 | Resistant | R539T |
| SA028149 | R1_60exp1 | Resistant | R539T |
| SA028150 | R1_60exp3 | Resistant | R539T |
| SA028151 | S_60exp3 | Sensitive | WT |
| SA028152 | S_60exp1 | Sensitive | WT |
| SA028153 | S_60exp2 | Sensitive | WT |
| SA028154 | URBCS_exp4 | Uinfected red blood cells | Control |
| SA028155 | URBCS_exp3 | Uinfected red blood cells | Control |
| SA028156 | URBCS_exp2 | Uinfected red blood cells | Control |
| SA028157 | URBCS_exp1 | Uinfected red blood cells | Control |
| Showing results 1 to 13 of 13 |