Summary of Study ST002314
This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR001484. The data can be accessed directly via it's Project DOI: 10.21228/M8WT54 This work is supported by NIH grant, U2C- DK119886.
See: https://www.metabolomicsworkbench.org/about/howtocite.php
This study contains a large results data set and is not available in the mwTab file. It is only available for download via FTP as data file(s) here.
| Study ID | ST002314 |
| Study Title | Differential requirements for mitochondrial electron transport chain components in the adult murine liver - Lactate/Pyruvate Tolerance Test |
| Study Summary | Hepatic Cox10 knockout mice were injected with a lactate/pyruvate (10:1) solution with 40% of the mixture labeled with [U-13C]. After 30 minutes, plasma and liver tissue was harvested. Metabolites were extracted, dried, and derivatized to form methoxime-TBDMS adducts. |
| Institute | University of Texas Southwestern Medical Center at Dallas |
| Department | Children's Research Institute |
| Laboratory | Prashant Mishra |
| Last Name | Lesner |
| First Name | Nicholas |
| Address | 6000 Harry Hines BLVD |
| nicholas.lesner@pennmedicine.upenn.edu | |
| Phone | 2146483784 |
| Submit Date | 2022-08-22 |
| Num Groups | 2 |
| Total Subjects | 9 |
| Raw Data Available | Yes |
| Raw Data File Type(s) | d |
| Analysis Type Detail | GC-MS |
| Release Date | 2022-11-02 |
| Release Version | 1 |
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Collection:
| Collection ID: | CO002393 |
| Collection Summary: | Liver was frozen on liqN2. Liver was crushed on liqN2, and metabolites extracted with 80% meOH. MeOH was dried, and samples derivatized to form methoxime-TBDMS adducts and immediately injected onto the GCMS. |
| Sample Type: | Liver |
