Summary of Study ST003636
This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR002243. The data can be accessed directly via it's Project DOI: 10.21228/M8PR8Q This work is supported by NIH grant, U2C- DK119886.
See: https://www.metabolomicsworkbench.org/about/howtocite.php
This study contains a large results data set and is not available in the mwTab file. It is only available for download via FTP as data file(s) here.
| Study ID | ST003636 |
| Study Title | Individual glycemic responses to carbohydrates vary and reflect underlying metabolic physiology (metabolomics) |
| Study Summary | We measured PPGRs using continuous glucose monitoring (CGM) in 55 well-phenotyped participants challenged with seven different carbohydrates administered in replicate under standardized conditions. Plasma sample were collected at baseline visit for metabolomics. The ClinicalTrials.gov registration identifier is NCT03919877. |
| Institute | Stanford University |
| Last Name | Michael |
| First Name | Snyder |
| Address | 300 Pasteur Drive, M-344A Stanford, California 94305 |
| mpsnyder@stanford.edu | |
| Phone | (650) 723-4668 |
| Submit Date | 2024-11-17 |
| Raw Data Available | Yes |
| Raw Data File Type(s) | raw(Thermo) |
| Analysis Type Detail | LC-MS |
| Release Date | 2025-01-14 |
| Release Version | 1 |
Select appropriate tab below to view additional metadata details:
Combined analysis:
| Analysis ID | AN005969 | AN005970 | AN005971 | AN005972 |
|---|---|---|---|---|
| Analysis type | MS | MS | MS | MS |
| Chromatography type | HILIC | HILIC | Reversed phase | Reversed phase |
| Chromatography system | Thermo Q Exactive HF | Thermo Q Exactive HF | Thermo Q Exactive | Thermo Q Exactive |
| Column | Merck ZIC-HILIC column (100 x 2.1 mm, 3.5μm, 200Å) | Merck ZIC-HILIC column (100 x 2.1 mm, 3.5μm, 200Å) | Agilent Zorbax SBaq column (50 x 2.1 mm, 1.7μm, 100Å) | Agilent Zorbax SBaq column (50 x 2.1 mm, 1.7μm, 100Å) |
| MS Type | ESI | ESI | ESI | ESI |
| MS instrument type | Orbitrap | Orbitrap | Orbitrap | Orbitrap |
| MS instrument name | Thermo Q Exactive HF hybrid Orbitrap | Thermo Q Exactive HF hybrid Orbitrap | Thermo Q Exactive Orbitrap | Thermo Q Exactive Orbitrap |
| Ion Mode | POSITIVE | NEGATIVE | POSITIVE | NEGATIVE |
| Units | intensity | intensity | intensity | intensity |
Chromatography:
| Chromatography ID: | CH004535 |
| Instrument Name: | Thermo Q Exactive HF |
| Column Name: | Merck ZIC-HILIC column (100 x 2.1 mm, 3.5μm, 200Å) |
| Column Temperature: | 40℃ |
| Flow Gradient: | Details in the attachment |
| Flow Rate: | 0.5 mL/min |
| Internal Standard: | Yes |
| Solvent A: | 50% Acetonitrile/50% Water; 10mM Ammonium acetate |
| Solvent B: | 95% Acetonitrile/5% Water;10 mM ammonium acetate |
| Chromatography Type: | HILIC |
| Chromatography ID: | CH004536 |
| Instrument Name: | Thermo Q Exactive |
| Column Name: | Agilent Zorbax SBaq column (50 x 2.1 mm, 1.7μm, 100Å) |
| Column Temperature: | 60℃ |
| Flow Gradient: | Details in the attachment |
| Flow Rate: | 0.6 mL/min |
| Internal Standard: | Yes |
| Solvent A: | 100% Water; 0.06% Acetic acid |
| Solvent B: | 100% Methanol; 0.06% Acetic acid |
| Chromatography Type: | Reversed phase |
