Summary of Study ST001437

This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench,, where it has been assigned Project ID PR000988. The data can be accessed directly via it's Project DOI: 10.21228/M80680 This work is supported by NIH grant, U2C- DK119886.


This study contains a large results data set and is not available in the mwTab file. It is only available for download via FTP as data file(s) here.

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Study IDST001437
Study TitleSub-nanoliter metabolomics via mass spectrometry to characterize volume-limited samples - EBC
Study SummaryThe human metabolome provides a window into the mechanisms and biomarkers of various diseases. However, because of limited availability, many sample types are still difficult to study by metabolomic analyses. Here, we present a new mass spectrometry (MS)-based metabolomics strategy that only consumes sub-nanoliter sample volumes. The approach consists of combining a customized metabolomics workflow with a pulsed MS ion generation method, known as triboelectric nanogenerator inductive nanoelectrospray ionization (TENGi nanoESI) MS. The first set of samples tested for this approach included exhaled breath condensates (EBC) collected from cystic fibrosis (CF) patients with impaired glucose tolerance to study the metabolome changes before and after the oral glucose tolerance test.
Georgia Institute of Technology
Last NameFacundo
First NameFernandez
Address901 Atlantic Dr NW
Phone(404) 385-4432
Submit Date2020-07-29
Raw Data AvailableYes
Raw Data File Type(s)raw(Waters)
Analysis Type DetailMS(Dir. Inf.)
Release Date2020-09-14
Release Version1
Fernandez Facundo Fernandez Facundo application/zip

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Combined analysis:

Analysis ID AN002401
Analysis type MS
Chromatography type None (Direct infusion)
Chromatography system none
Column none
MS instrument type QTOF
MS instrument name Waters Synapt G2 S QTOF
Units Normalized Intensity (Intensity ratio against internal standard signal))


Chromatography ID:CH001764
Instrument Name:none
Column Name:none
Chromatography Type:None (Direct infusion)