Summary of Study ST003220

This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR002008. The data can be accessed directly via it's Project DOI: 10.21228/M8281N This work is supported by NIH grant, U2C- DK119886.

See: https://www.metabolomicsworkbench.org/about/howtocite.php

This study contains a large results data set and is not available in the mwTab file. It is only available for download via FTP as data file(s) here.

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Study IDST003220
Study TitleObesity, sex, and depot drive distinct lipid profiles in murine white adipose tissue
Study SummaryTo investigate how the lipid composition of the adipose tissue changes with obesity, sex, and depot, we performed comprehensive untargeted lipidomics on the whole adipose tissue of the inguinal and perigonadal adipose depot from lean and obese, male and female mice. The screen allowed us to identify lipid signatures sufficient to differentiate different adipose tissue samples. Such that, increased levels of OxTG and CL, increase in DG and Cer, and increase in HexCer were all able to differentiate adipose tissue based on obesity, sex, or depot, respectively.
Institute
University of Utah
Last NameHilgendorf
First NameKeren
AddressEEJMRB 5520
Emailkeren.hilgendorf@biochem.utah.edu
Phone(801) 587-1071
Submit Date2023-10-25
Raw Data AvailableYes
Raw Data File Type(s)mzML
Analysis Type DetailLC-MS
Release Date2024-06-12
Release Version1
Keren Hilgendorf Keren Hilgendorf
https://dx.doi.org/10.21228/M8281N
ftp://www.metabolomicsworkbench.org/Studies/ application/zip

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Combined analysis:

Analysis ID AN005280 AN005281
Analysis type MS MS
Chromatography type Reversed phase Reversed phase
Chromatography system Agilent 1290 Infinity Agilent 1290 Infinity
Column Waters ACQUITY UPLC CSH C18 (100 x 2.1mm,1.7um) Waters ACQUITY UPLC CSH C18 (100 x 2.1mm,1.7um)
MS Type ESI ESI
MS instrument type QTOF QTOF
MS instrument name Agilent 6545 QTOF Agilent 6545 QTOF
Ion Mode POSITIVE NEGATIVE
Units pmol/mg tissue pmol/mg tissue
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