Return to study ST002298 main page

MB Sample ID: SA221033

Local Sample ID:urine_44303
Subject ID:SU002384
Subject Type:Mammal
Subject Species:Rattus norvegicus
Taxonomy ID:10116

Select appropriate tab below to view additional metadata details:


Treatment ID:TR002396
Treatment Summary:According to the National Institutes of Health Guide for the Care and Use of Laboratory Animals, all animals involved in this study were cared for, and protocols were reviewed and approved by the Anhui Laboratory Animal Care Committee. The specific pathogen-free (SPF) seven-week-old male Sprague Dawley (SD) rats (weight 233 ± 5 g) were purchased from Beijing Vital River Laboratory Animal Technology Co., Ltd and used in this study. The environmental conditions were set at 21-26°C with a relative humidity of 50 ± 10% and a 12/12 h light/dark cycle. Food and tap water were provided ad libitum, and body weights were recorded daily. After one week of acclimatization, rats were randomly assigned to the groups of non-stressed control (n = 6) or the stressed (n = 7). For restraint stress, rats were individually placed in a ventilated plastic tube restrainer for 120 minutes, using a previously modified method. According to the general protocol, control rats were left undistributed in a home cage and allowed to contact each other without food and water.