Summary of project PR001772

This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench,, where it has been assigned Project ID PR001772. The data can be accessed directly via it's Project DOI: 10.21228/M8NT5Z This work is supported by NIH grant, U2C- DK119886.


Project ID: PR001772
Project DOI:doi: 10.21228/M8NT5Z
Project Title:L-isoleucine in P10 STZ (Streptozotocin)
Project Summary:The effects of intraperitoneal L-isoleucine injection in murine hyperglycemia-associated retinopathy, a model mimicking aspects of retinopathy of prematurity (ROP), will be studied. ROP is a leading cause of blindness in children worldwide. Amino acid metabolism is altered in preterm infants. In this study, pups were daily injected with streptozotocin from P1 to P10 to induce hyperglycemia-associated retinopathy. L-isoleucine or PBS control was injected intraperitoneally from P7 to P10. Retinas were collected at P10. 8 retinas (from 4 pups) were pooled to generate 1 sample. 3 samples per group will be compared.
Institute:Boston Childrens Hospital
Last Name:Fu
First Name:Zhongjie
Address:1 Blackfan Circle, Boston, MA 02114

Summary of all studies in project PR001772

Study IDStudy TitleSpeciesInstituteAnalysis
(* : Contains Untargted data)
(* : Contains raw data)
ST002830 L-isoleucine in P10 STZ Mus musculus Boston Childrens Hospital MS 2023-09-14 1 15 Uploaded data (399.5M)*