Summary of project PR001423

This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench,, where it has been assigned Project ID PR001423. The data can be accessed directly via it's Project DOI: 10.21228/M8SD86 This work is supported by NIH grant, U2C- DK119886.


Project ID: PR001423
Project DOI:doi: 10.21228/M8SD86
Project Title:Batch variation of large scale LC-MS metabolomics analysis of human plasma samples
Project Summary:Metabolomics holds the promise to measure and quantify small molecules comprehensively in biological systems, and LC-MS (liquid chromatography coupled mass spectrometry) has become the leading technology in the field. Significant challenges still exist in the computational processing of data from LC-MS metabolomic experiments into metabolite features, including provenance and reproducibility of the current software tools. Current dataset, named HZV029, comprises of 268 data files, from two QC (human pooled plasma) samples that were analyzed repeatedly over 17 batches, on a Thermo Scientific Orbitrap ID-X Tribrid mass spectrometer, coupled with dual liquid chromatography via a Transcend LX-2 System. It provides a unique opportunity to be used as a benchmark dataset to evaluate reproducibility via available choices of different processing tools without knowing the ground truth about these QC samples.
Institute:The Jackson Laboratory For Genomic Medicine
Laboratory:Shuzhao Li Lab
Last Name:Siddiqa
First Name:Amnah
Address:10 Discovery Drive , Farmington, CT 06032
Phone:404-918 7223
Funding Source:1R01AI149746 (NIH-NIAID)

Summary of all studies in project PR001423

Study IDStudy TitleSpeciesInstituteAnalysis
(* : Contains Untargted data)
(* : Contains raw data)
ST002233 Batch variation of large scale LC-MS metabolomics analysis of human plasma samples Homo sapiens The Jackson Laboratory for Genomic Medicine MS* 2022-11-01 1 268 Uploaded data (9.5G)*