Summary of project PR001178

This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench,, where it has been assigned Project ID PR001178. The data can be accessed directly via it's Project DOI: 10.21228/M8F99F This work is supported by NIH grant, U2C- DK119886.


Project ID: PR001178
Project DOI:doi: 10.21228/M8F99F
Project Title:Systemic metabolic responses to hypoxia
Project Summary:Prolonged cellular hypoxia leads to energetic failure and death. However, sublethal hypoxia can trigger an adaptive response called hypoxic preconditioning. While prolyl-hydroxylase (PHD) enzymes and hypoxia inducible factors (HIFs) have been identified as key elements of oxygen sensing machinery, the mechanisms by which hypoxic preconditioning protects against insults remain unclear. Here, we perform serum metabolomic profiling to assess alterations induced by hypoxic preconditioning.
Institute:Northwestern University, Feinberg School of Medicine
Last Name:Kapitsinou
First Name:Pinelopi
Address:303 East Superior Street, Chicago, Il, 60611, USA

Summary of all studies in project PR001178

Study IDStudy TitleSpeciesInstituteAnalysis
(* : Contains Untargted data)
(* : Contains raw data)
ST001865 Systemic metabolite changes due to Hypoxia Mus musculus Northwestern University MS 2022-01-02 1 16 Not available
ST001866 Systemic metabolite changes due to PHD inhibition Mus musculus Northwestern University MS 2022-01-02 1 14 Not available