Summary of project PR001129

This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench,, where it has been assigned Project ID PR001129. The data can be accessed directly via it's Project DOI: 10.21228/M8RX1D This work is supported by NIH grant, U2C- DK119886.


Project ID: PR001129
Project DOI:doi: 10.21228/M8RX1D
Project Title:Plasma metabolomics of diverse mouse strains infected with Plasmodium chabaudi
Project Summary:To uncover links between metabolism and disease severity in murine malaria, we performed plasma metabolomics via Metabolon on eight inbred, Plasmodium chabaudi-infected mouse strains with diverse disease phenotypes. We sacrificed and collected plasma from >=3 mice per strain per day of acute infection alongside uninfected control mice (approximately days 5-12 depending on mouse strain). We collected disease severity data, e.g. weight loss, liver enzymes, and anemia, concurrently. Together, these data enable 1) a picture of strain-specific and conserved metabolic responses during acute malaria, and 2) a comparison between metabolic responses and disease severity.
Institute:Stanford University
Department:Microbiology & Immunology
Laboratory:David Schneider
Last Name:Schneider
First Name:David
Address:299 Campus Drive

Summary of all studies in project PR001129

Study IDStudy TitleSpeciesInstituteAnalysis
(* : Contains Untargted data)
(* : Contains raw data)
ST001775 Plasma metabolomics of diverse mouse strains infected with Plasmodium chabaudi Mus musculus Stanford University MS 2021-05-21 1 369 Not available